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The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure response during exercise.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sham arm | Sham Comparator | Perform inspiratory muscle training at 2% maximal inspiratory pressure for 12 weeks. |
|
| Non-sham arm | Active Comparator | Perform inspiratory muscle training at 40% maximal inspiratory pressure for 12 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Inspiratory muscle training | Device | Inspiratory muscle training for 12 weeks at 40% maximal inspiratory pressure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure response | Mean arterial pressure | baseline and 12 week follow up |
| Change in blood flow response | respiratory muscle blood flow | baseline and 12 week follow up |
| Change in limb vascular resistance response | Limb vascular resistance | baseline and 12 week follow up |
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Inclusion Criteria - Heart Failure Group:
Inclusion Criteria - Healthy Control Group:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eric Bruhn, MA | Contact | 507-266-2690 | bruhn.eric@mayo.edu | |
| Joshua Smith | Contact | smith.joshua1@mayo.edu |
| Name | Affiliation | Role |
|---|---|---|
| Joshua Smith, PhD | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic in Rochester | Recruiting | Rochester | Minnesota | 55905 | United States |
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| Label | URL |
|---|---|
| Mayo Clinic Clinical Trials | View source |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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