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Hypoxia in single lung ventilation versus two lung ventilation in video assisted lung surgeries
Incidence of hypoxia in single lung ventilation by double lumen endotracheal tube "of choice in lung surgeries" versus incidence of hypoxia in two lung ventilation by conventional single lumen endotracheal tube "intermittent two lung ventilation"
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Single lung ventilation | Active Comparator | Using double lumen endotracheal tube and lung isolation |
|
| Two lung ventilation | Active Comparator | Using conventional single lumen endotracheal tube and intermittent two lung ventilation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Single lung ventilation by double lumen endotracheal tube | Procedure | Single lung ventilation using double lumen endotracheal tube and isolation of the operated lung during surgery to create ideal surgical field |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of hypoxemia | Hypoxemia in single and two lung ventilation by serial arterial blood gases | Intraoperative to first 24 hours post operative |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of failure to correct Hypoxemia in single lung ventilation | Stop lung isolation and procedure using two lung ventilation to correct hypoxia | Intraoperative |
| Incidence of failure of two lung ventilation to create optimum surgical field |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Esraa Abdellatif | Contact | 01119895491 | esraa301993@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Esraa Abdellatif, M.B., B.Ch. | Anesthesiology department | Principal Investigator |
| Omar El safty, MD | Anesthesiology department | Study Chair |
| Salwa Omar, MD |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aun Shams University Hospitals | Recruiting | Cairo | Egypt |
All study data will be open to other researchers
After finishing the study by the end of August 2021
For any medical student or staff interested in topic without any other considerations
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Oct 3, 2021 | |
| Reset | Nov 1, 2021 | |
| Release | Jun 26, 2022 | |
| Unrelease | Aug 10, 2022 |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Jan 1, 2021 | Mar 18, 2021 | Prot_SAP_000.pdf |
| ICF | No | No | Yes | Informed Consent Form | Jan 1, 2021 | Jul 19, 2021 | ICF_001.pdf |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Oct 3, 2021 | Nov 1, 2021 | |||
| Jun 26, 2022 | Aug 10, 2022 |
| ID | Term |
|---|---|
| D000860 | Hypoxia |
| ID | Term |
|---|---|
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Two equal groups: the first group undergoing lung surgeries with single lung ventilation by double lumen endotracheal tube, the second group undergoing lung surgeries with two lung ventilation using conventional single lumen endotracheal tube
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The patients will not know whether they are in the first or second group
| Two lung ventilation by conventional single lumen endotracheal tube | Procedure | Intermittent two lung ventilation so that no significant hypoxia occurs with creating optimum surgical field |
|
Frequent stopping of ventilation and the surgent can't access the surgical field easily
| Intraoperative |
| Incidence of post operative complications | Any associated complications | First 24 hours post operative |
| Anesthesiology department |
| Study Director |
| Mohamed Taeimah, MD | Anesthesiology department | Study Director |