The purpose of this research study is to explore the relationship between the gut microbiome and hormone levels in women diagnosed with PCOS and determine whether there are differences in the gut microbiome between women with PCOS and women without PCOS.

Consented, enrolled participants will complete a health questionnaire, complete a fasted blood draw at a local laboratory, and provide a stool, saliva, and vaginal swab sample for comprehensive biomarkers, hormones, metagenomics, and metabolomics analysis.

Inclusion Criteria:

• Women diagnosed with PCOS or Women who are considered Healthy
• 18-40 years old
• Residing in the USA, except for exclusion states
• Have not been using hormonal therapy for at least 3 months

Exclusion Criteria:

• Women using hormonal therapy within the last 3 months
• Diagnosed with other significant health conditions or using medications that will affect hormone levels
• Residing in NY, NJ, MD, RI, ND, SD, or HI
• Pregnant or nursing

Women, ages 18-40, living in the USA (except for NY, NJ, RI, MD, SD, ND, or HI), who have not been using hormonal therapy for at least 3 months and without other significant health issues or medications affecting hormones. Women must be previously diagnosed with PCOS or considered Healthy and not currently pregnant or nursing. Women will be referred to the study by their Physician or word of mouth.