This study is intended to demonstrate the superiority of colorectal polyp detection using computer-assisted colonoscopy compared to conventional colonoscopy.

Inclusion Criteria:

• Average risk subjects undergoing their first colonoscopy (screening) or follow-up colonoscopy for previous history of polyps (surveillance interval of 3 years or greater)
• Patients aged 45 or older
• Patients who can provide an informed consent

Exclusion Criteria:

• Patients with history of colon resection, Inflammatory Bowel Disease (IBD), Familial Adenomatous Polyposis (FAP), severe comorbidity, including end-stage cardiovascular/pulmonary/liver/renal disease
• Patients who are pregnant or are planning pregnancy during study period
• Patients who are not able to or refuse to give informed consent

Patients will be randomized 1:1, inspection with computer assisted colonoscopy: inspection with conventional colonoscopy.