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This is a pathogenic mutation profile of colorectal patients specifically in 5 genes, i.e. APC, TP53, PIK3CA, KRAS, and MLH1. Single nucleotide variants identified were synchronized with patients' characteristics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Age |
| ||
| Grade |
| ||
| Tumor location |
| ||
| Stage |
| ||
| Lymphovascular invasion |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| co-occuring mutation | Other | APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA |
|
| Measure | Description | Time Frame |
|---|---|---|
| Description of clinical characteristics | Age, gender | January 2017 - June 2021 |
| Description of tumor nature | grade, stage, lymphovascular invasion, tumor location | January 2017 - June 2021 |
| Description of survival | Median of life expectancy | January 2017 - June 2021 |
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Inclusion Criteria:
Exclusion Criteria:
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This is a descriptive study in patients with colorectal malignancies who underwent surgery and/or chemoradiation and/or chemotherapy at RSCM, RSKJ, and MRCCC in 2017-2018 whose tumor tissue specimens were still properly stored in the form of formalin-fixed paraffin-embedded (FFPE). .
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Vania Myralda Giamour Marbun | Jakarta | ALL | 12740 | Indonesia |
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |