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To compare preoxygenation for induction of general anaesthesia with High Flow Nasal Cannula vs preoxygenation with face mask in patients undergoing bariatric surgery. The hypothesis is that preoxygenation with High Flow Nasal Cannula prolongs normoxia time during induction of anaeshesia and is superior to conventional preoxygenation with face mask. Primary endpoint will be the time during which spO2 > 92 %. Secondary endpoint will be paCO2.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Preoxygenation via THRIVE/High Flow Nasal Cannula | Experimental | Patients receive preoxygenation for induction of general anaesthesia via High Flow Nasal Cannula for the duration of 5 minutes. After that the induction agents will be given. Now arterial blood gases will be drawn every 2 minutes and the SpO2 will be measured until the 6th apnoeic ABG or if the SpO2 decreases to 92%. After that normal intubation follows. |
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| Preoxygenation via face mask (PROX) | Active Comparator | Patients receive preoxygenation for induction of general anaesthesia via tight fitting face mask for the duration of 5 minutes. After that the induction agents will be given. Now arterial blood gases will be drawn every 2 minutes and the SpO2 will be measured until the 6th apnoeic ABG or if the SpO2 decreases to 92%. After that normal intubation follows. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Preoxygenation with High Flow Nasal Cannula | Other | Preoxygenation for 5 minutes via High Flow Nasal Cannula. After induction of anaesthesia apnoeic oxygenation with HFNC |
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| Measure | Description | Time Frame |
|---|---|---|
| Normoxia time SpO2 > 92% | Time in which the SpO2 remains > 92% while patient is apnoeic | 10 Minutes after induction |
| Measure | Description | Time Frame |
|---|---|---|
| paCO2 | Increase in arterial CO2 during Apnoea | 10 Minutes after induction |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Joachim Jugl | Contact | 004972197467846 | Joachim.Jugl@klinikum-karlsruhe.de | |
| Franz Kehl, Prof. | Contact | 00497219741601 |
| Name | Affiliation | Role |
|---|---|---|
| Joachim Jugl | Senior Resident Anaesthesia | Principal Investigator |
| Franz Kehl, Prof. | Head of Department of Anaesthesia and Intensive Care | Study Director |
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Two groups of patients. One receiving preoxygenation via High Flow Nasal Cannula and one group receiving preoxygenation via face mask
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Patients will be divided into two groups by lot.
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| Preoxygenation via face mask | Other | Preoxygenation for 5 minutes via face mask. After induction of anaesthesia apnoeic oxygenation with tight fitting face mask |
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