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| Name | Class |
|---|---|
| Second Affiliated Hospital, School of Medicine, Zhejiang University | OTHER |
| Shanghai Zhongshan Hospital | OTHER |
| Henan Provincial People's Hospital | OTHER |
The aims of this study are to 1. Evaluate the right heart structure and function in T2DM and Prediabetes patients by speckle tracking echocardiography, and to further investigate the influence of left heart on right heart structure and function in T2DM and Prediabetes patients. 2. To explore the prognostic value of right ventricular function in T2DM patients.
This study will recruit 1000 T2DM patients and 500 Prediabetes and 500 healthy controls. Assessing the left heart and right heart structure and function by speckle tracking echocardiography. Patients with T2DM were followed up for adverse cardiovascular outcome events (myocardial infarction, cerebrovascular stroke, or cardiovascular death, hospitalization for heart failure). And the study aimed to 1. 1. Evaluate the right heart structure and function in T2DM and Prediabetes patients by speckle tracking echocardiography, and to further investigate the influence of left heart on right heart structure and function in T2DM and Prediabetes patients. 2. To explore the prognostic value of right ventricular function in T2DM patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| type 2 diabetes | T2DM was defined according to the WHO 2006 criteria. Assessing the left heart and right heart structure and function of T2DM by speckle tracking echocardiography. | ||
| Prediabetes | According to the WHO 2006 criteria, combining impaired fasting glucose and impaired glucose tolerance as prediabetes. Assessing the left heart and right heart structure and function of prediabetes by speckle tracking echocardiography. | ||
| normal glucose metabolism(NGM) | Assessing the left heart and right heart structure and function of NGM by speckle tracking echocardiography. |
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| Measure | Description | Time Frame |
|---|---|---|
| major adverse cardiovascular events | including myocardial infarction, cerebrovascular stroke, or cardiovascular death, hospitalization for heart failure | through study completion, an average of 6 year |
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Inclusion Criteria:
people with T2DM according to the WHO 2006 criteria
Exclusion Criteria:
including history or symptoms of CAD valvular heart disease, rhythm disturbances cardiomyopathy congenital heart disease symptomatic heart failure pulmonary disease
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All patients with type 2 diabetes mellitus and prediabetes were diagnosed according to the WHO 2006 criteria, aged 35 -79 years, who are undergoing echocardiography examination in clinical needs.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jing Wang, PhD | Contact | 13397105628 | 2419676@qq.com | |
| Li Zhang, PhD | Contact | 18907131488 | zli429@hust.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Jing Jing, PhD | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Principal Investigator |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| Wuhan Asia Heart Hospital |
| OTHER |
| Guangdong Provincial People's Hospital | OTHER |
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