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Pneumoconiosis is relatively prevalent in low/middle-income countries, and it remains a challenging task to accurately and reliably diagnose pneumoconiosis. The investigators implemented a deep learning solution and clarified the potential of deep learning in pneumoconiosis diagnosis by comparing its performance with two certified radiologists. The deep learning demonstrated a unique potential in classifying pneumoconiosis.
The investigators retrospectively collected a dataset consisting of 1881 chest X-ray images in the form of digital radiography. These images were acquired in a screening setting on subjects who had a history of working in an environment that exposed them to harmful dust. Among these subjects, 923 were diagnosed with pneumoconiosis, and 958 were normal. To identify the subjects with pneumoconiosis, the investigators applied a classical deep convolutional neural network (CNN) called Inception-V3 to these image sets and validated the classification performance of the trained models using the area under the receiver operating characteristic curve (AUC).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| convolutional neural network (CNN) | a classical deep convolutional neural network (CNN) called Inception-V3 was applied to the image sets and validated the classification performance of the trained models |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| convolutional neural networks (CNNs) | Other | CNN architecture named U-Net architecture |
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| Measure | Description | Time Frame |
|---|---|---|
| the diagnosis of pneumoconiosis | The diagnosis and staging of pneumoconiosis were made by an expert panel consisting of certified radiologists and occupational physicians. The diagnosis of pneumoconiosis was confirmed by medical history and previous medical records(chest X-rays and pulmonary function testing). | up to 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Of these subjects, 923 were diagnosed with pneumoconiosis, 958 were normal. Among these subjects, 163 were females.
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| Name | Affiliation | Role |
|---|---|---|
| Xiaohua Wang | Peking University Third Hospital | Study Chair |
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| ID | Term |
|---|---|
| D011009 | Pneumoconiosis |
| ID | Term |
|---|---|
| D017563 | Lung Diseases, Interstitial |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D055370 | Lung Injury |
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| ID | Term |
|---|---|
| D000098415 | Convolutional Neural Networks |
| ID | Term |
|---|---|
| D016571 | Neural Networks, Computer |
| D055641 | Mathematical Concepts |
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| D009784 |
| Occupational Diseases |