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There are few studies about immunological explorations in COPD. Because of the complications of lung biopsies, analyses are generally made on blood samples instead of lung tissue. No study tried to classify COPD vs Asthma vs ACOS. The investigators wondered if there were differences in biomarkers between these groups. The investigators decided to open a pilot-study among COPD patients followed in Amiens-University Hospital. Each patient will be examined and a blood-test will be performed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| frequent exacerbation patients |
| ||
| non frequent exacerbation patients |
| ||
| Asthma-and-COPD overlap syndrome |
| ||
| Asthmatic patients (without COPD) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physical examinations | Other | BPCO physical examinations |
|
| Measure | Description | Time Frame |
|---|---|---|
| identification specific blood immunologic marker for COPD | COPD biomarkers are blood immunologic markers | one hour |
| Measure | Description | Time Frame |
|---|---|---|
| Complete blood count (CBC) Variation between COPD and asthmatic patients | one hour | |
| c-reactive protein concentration variation between COPD and asthmatic patients | one hour | |
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Inclusion Criteria:
Exclusion Criteria:
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chronic obstructive pulmonary disease (COPD) patients, followed in Amiens-University Hospital
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Amiens | Amiens | 80480 | France |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D000080445 | Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome |
| D001249 | Asthma |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| ID | Term |
|---|---|
| D012149 | Restraint, Physical |
| D006403 | Hematologic Tests |
| ID | Term |
|---|---|
| D032763 | Behavior Control |
| D013812 | Therapeutics |
| D007103 | Immobilization |
| D008919 | Investigative Techniques |
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Blood sample
| blood test | Diagnostic Test | blood test in order to study immunologic markers |
|
| Plasma protein electrophoresis profile Variation between COPD and asthmatic patients |
| one hour |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001982 | Bronchial Diseases |
| D012130 | Respiratory Hypersensitivity |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D006969 | Hypersensitivity, Immediate |
| D019411 |
| Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |