Effects of Anti-VEGF Targeted Drugs on Patients' Blood Pressure and Endothelial Function

Effects of Anti-VEGF Targeted Drugs on Patients' Blood Pressure and Endothelial Function

Explore the effects of anti-VEGF targeted drugs on blood pressure and endothelial function in cancer patients.

Thirty tumor patients with anti-VEGF drugs were selected. Demographic information and clinical information of all patients were collected before chemotherapy. Ambulatory blood pressure monitoring and endothelial function measurement (PWV, EndoPAT) were performed. Ambulatory blood pressure and PWV were reviewed at 2 weeks and 1 month. And EndoPAT, to evaluate the effects of anti-VEGF drugs on blood pressure and endothelial function in cancer patients.

Inclusion Criteria:

• Tumor patients using anti-VEGF drugs

Exclusion Criteria:

• Hypertension, coronary heart disease, valvular heart disease, cardiomyopathy and other organic heart diseases, exclude liver and kidney failure, severe cerebrovascular disease, chronic obstructive pulmonary disease, rheumatic immune system disease