A Phase III, Randomized, Open-Label, Multicenter Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Patients With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer
A Phase III, Randomized, Open-Label, Multicenter Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Patients With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer
This is a Phase III, global, randomized, open-label, multicenter, study evaluating the efficacy and safety of adjuvant giredestrant compared with physician's choice of endocrine therapy in participants with medium- and high-risk Stage I-III histologically confirmed estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative early breast cancer.
Inclusion Criteria:
Exclusion Criteria:
Bakersfield, California 93309, United States
Orange, California 92868, United States
Saint Louis Park, Minnesota 55426, United States
Winston-Salem, North Carolina 27157, United States
Roanoke, Virginia 24014, United States
Buenos Aires, Ciudad Autónoma de BuenosAires C1113AAE, Argentina
Caba, C1426AGE, Argentina
Ciudad Autonoma Buenos Aires, C1426ABP, Argentina
Provincia de Tucumán, T4000, Argentina
San Juan, J5402DIL, Argentina
Belgium, 1000, Belgium
Cachoeiro de Itapemirim, Espírito Santo 29308-014, Brazil
Salvador, Bahia, Estado de Bahia 40170-380, Brazil
Salvador/BA, Estado de Bahia 41820-021, Brazil
Caixas Do Sul, Rio Grande do Sul 95070-560, Brazil
Porto Alegre, Rio Grande do Sul 90050-170, Brazil
São José do Rio Preto, São Paulo 15090-000, Brazil
São Paulo, 01246-000, Brazil
São Paulo, 0317-0001, Brazil
Chicoutimi, Quebec G7H 5H6, Canada
Providencia, Región-MetropolitanadeSantiago 7500000, Chile
Hangzhou, Zhejiang 310002, China
Wuhan, 430023, China
Wuhan, 430030, China
Markaz Sohag, 82511, Egypt
Brest, 29200, France
Athens, 115 27, Greece
Faliro, 185 47, Greece
Faliro, 185 47, Greece
Zalaegersteg, 8900, Hungary
Patna, Bihar 800014, India
Ratnagiri Kilminnal, Tamil Nadu 632517, India
Kolkata, West Bengal 700020, India
Beer Jacob, 0073100, Israel
Avellino, Campania 83100, Italy
Naples, Campania 80131, Italy
Meldola, Emilia-Romagna 47014, Italy
Roma, Emilia-Romagna 00168, Italy
Milan, Lombardy 20162, Italy
Isehara-Shi, Kanagawa 259-1193, Japan
Kumamoto-Shi Chuo-Ku, Kumamoto 860-0811, Japan
Osaka-Shi Chuo-Ku, Osaka 540-0006, Japan
Koto-Ku, Tokyo 135-0063, Japan
Kitaadachi-gun, 362-0806, Japan
R?ga, LV-1002, Latvia
Buzia?, Sarawak 305100, Malaysia
Petaling Jaya, Selangor, Selangor 46050, Malaysia
Mexicali, Estado de Baja California 21200, Mexico
Gliwice, 44-101, Poland
Warsaw, 02-781, Poland
Lisbon, Lisbon District 1649-035, Portugal
Bucure?ti, 011171, Romania
Timi?oara, 300595, Romania
City of Johannesburg, 2196, South Africa
Cheonan-si, Chungcheongnam-do 330721, South Korea
Gangwon-do, 26426, South Korea
Namdong-Gu, 21565, South Korea
Seongbuk-Gu, 02841, South Korea
Songpa-Gu, 05505, South Korea
Castellon de LA Plana/castello de LA Plana, Castellon 12002, Spain
S. Cristobal de La Laguna, Tenerife 38320, Spain
Changhua County, 50006, Taiwan
Xitun Dist., 40705, Taiwan
Pathumwan, Bangkok Metropolis 10330, Thailand
Sariçam, Adana 01250, Turkey (Türkiye)
Istanbul, 34722, Turkey (Türkiye)
Seyhan/Adana, 01130, Turkey (Türkiye)
Yen?mahalle, 06200, Turkey (Türkiye)
Chernihiv, KIEV Governorate 14029, Ukraine