Evaluation of Heidelberg Engineering SPECTRALIS OCT Signal to Noise Ratio Effect on Parameter Measurements

Evaluation of Heidelberg Engineering SPECTRALIS OCT Signal to Noise Ratio Effect on Parameter Measurements

Evaluation of effect of various OCT scan speeds and filters on parameter measurements.

The objectives of this study are to

1. Directly compare parameter measurements generated on scans acquired at different speed modes with various levels of signal-to-noise ratio (SNR).
2. Evaluate the effects of SNR, as determined by the device's Q score, on parameters derived from segmentation results, i.e., thickness of peripapillary retinal nerve fiber layer on circle scans (pRNFL), minimum rim width of optical nerve head (MRW), and macular layer thicknesses (Retina, GCL, IPL).

Inclusion Criteria:

1. Able and willing to undergo the test procedures, sign informed consent, and follow instructions.
2. Age ≥ 22
3. Both eyes with an age-appropriate normal appearing OCT as determined by an investigator

Exclusion Criteria:

1. Subjects unable to read or write
2. Subjects with ocular media not sufficiently clear to obtain acceptable study-related imaging as determined by OCT imaging (without neutral optical density filter)
3. Subjects who cannot tolerate the imaging procedures