This study intends to investigate the negative emotions, fear-avoidance beliefs, and quality of life in patients with chronic ankle sprains to explore the relationship between negative emotions such as anxiety and depression, fear-avoidance beliefs, and their impact on quality of life.

Research design: This study is an observational study. It is planned to recruit a total of 120 patients with ankle sprain injury who meet the selection criteria from the Rehabilitation Department of Peking University Third Hospital. They will be divided into an anxiety and depression group and a control group based on anxiety and depression scale. Basic information, anxiety and depression scales, fear-avoidance beliefs score and quality of life score of two groups will be compared and analyzed.

Inclusion Criteria:

• Ankle sports injury time> 6 months;
• age 18-50 years;
• no pain in daily activities, or a numerical rating scale (NRS) 6 points or less;
• no mechanical instability of the ankle joint and obvious restriction in joint movement ;
• agree to participate in this study.

Exclusion Criteria:

• acute inflammation of lower limb joints;
• new or unhealed lower limb fractures;
• history of lower limb surgery within 3 months;
• lower limb pain caused by other diseases (such as lumbar disease, vascular disease, etc.);
• speech and cognitive impairment
• other diseases that cannot participate in this study.

Ankle sprains are the most common injury in everyday life, military training and sports. Forty percent of people with ankle sprains develop chronic ankle instability, including mechanical ankle instability and functional ankle instability. Mechanical ankle instability is usually caused by structural changes in the ligamentous tissue around the ankle, kinematic damage, synovial changes or degenerative joint disease. Functional ankle instability refers to the subjective perception of instability during daily life or sports. Most patients do not require surgery, and clinical examination reveals only minor swelling and localized pressure pain, but rarely severe structural damage to the joint with limited range of motion and joint instability. However, many patients with chronic functional instability of the ankle joint due to ankle sprain are unable to resume normal work and life due to emotional anxiety and repeatedly seek medical attention.