Shear-wave Elastography Compared to Respiratory Function Testing

Comparison of Shear-wave Elastography to State-of-the-art Respiratory Function Testing to Measure the Range of Forces Generated by the Diaphragm Muscle

The purpose of this study is to evaluate the relationship between transdiaphragmatic pressure (Pdi) and diaphragm shear-wave elastography (SWE) during state-of-the-art respiratory muscle testing including volitional efforts (e.g., maximal inspiratory pressure, maximal expiratory pressure, Valsalva maneuver), as well as maximal phrenic nerve stimulation.

Inclusion Criteria:

- Adult male and female healthy volunteers.

Exclusion Criteria:

• Volunteers who are pregnant.
• Volunteers with known pulmonary pathology (COPD, asthma requiring routine treatment).