A Prospective Cohort Study on Familial Hypercholesterolemia in Health Examination Population

A Prospective Cohort Study on Familial Hypercholesterolemia in Health Examination Population

To determine the prevalence and the prognosis in a corhort of patients with familial hypercholesterolemia (FH).

This study aims to achieve the following goals through prospective cohort study and statistical analysis: (1) to determine the prevalence of familial hypercholesterolemia (FH) in healthy people with hypercholesterolemia.（2) Compared with non FH population, the relative risk of atherosclerotic cardiovascular disease (ASCVD) in FH patients in China was calculated, and the risk prediction model of ASCVD in FH patients was constructed by using biochemical results, imaging data, biomarkers and other indicators.（3) To evaluate the benefits of different lipid-lowering strategies for FH patients in China.（4) To analyze the gene carriers of FH patients in China.

Inclusion Criteria:

1) Patients with definite diagnosis of hyperlipidemia.

Exclusion Criteria:

1. Age < 18.
2. Do not agree to participate in this study.
3. secondary hypercholesterolemia.
4. Phytosteronemia.