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Ectopic pregnancy is an early pregnancy complication in which a fertilized ovum implant outside the uterine cavity. Implantation may occur anywhere along the reproductive tract with the most common implantation site being the fallopian tube. The incidence of ectopic pregnancy is 1% of pregnant women, and may seriously compromise women's health and future fertility.
Currently, ectopic pregnancy can be often diagnosed before the woman's condition has deteriorated, which has altered the former clinical picture of a lifethreatening disease into a more benign condition in frequently asymptomatic women.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Serum beta HCG | Diagnostic Test | Raising numbers of S BHCG or decreasing with different management of tubal Ectopic Pregnancy |
| Measure | Description | Time Frame |
|---|---|---|
| Abdominal and Transvaginal Ultrasound: | To detect the appearance of any mass at the adenexa,or intrauterine gestational sac in case of heterotopic pregnancy or misdiagnosis of ectopic pregnancy. To detect, if there's collection at the pelvis or freely at the abdomen in the case of disturbed ectopic pregnancy. | 6 Monthes |
| S.bHCG: | in cases of expectant management,and medical treatment to detect level of S.bHCG after administration of methotrexate to decide to continue with medical treatment and give another doses or failure of this line and decide another line of management. Also,at the expectant management to close follow up the patient. | 6 Monthes |
| Diagnostic laparoscopy | In cases of early,undisturbed ectopic pregnancy and may use also,for therapy Laparoscopic salpingostomy and/or salpingectomy | 6 Monthes |
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Inclusion criteria:
Exclusion criteria:
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Sample size: All articles fulfilling the inclusion criteria within the last five years.
Study tools: Primary data will be re-analyzed statistically and processed data to be compared. Secondary data will be analyzed for correlation between the type of anastomosis (hand sewing vs. staplers) and between measurements outcome (leakage and, stricture and fistula formation).
• Study procedure: The study will start by searching articles using the key words and then downloading papers that fulfill the inclusion criteria and excluding papers with exclusion criteria. These papers will be examined by the supervisors to make sure of finding the appropriate source of data and then I will start working with the statistical supervisor and put data on R-based software for meta-analysis and start conducting the study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mohamed A Mohamed, Master | Contact | 01060386207 | mohamed011161@med.sohag.edu.eg | |
| Yasser A Helmy, Professor | Contact |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag | Recruiting | Akhmīm | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19625718 | Background | Barnhart KT. Clinical practice. Ectopic pregnancy. N Engl J Med. 2009 Jul 23;361(4):379-87. doi: 10.1056/NEJMcp0810384. No abstract available. | |
| 2548568 | Background | Bagshawe KD, Dent J, Newlands ES, Begent RH, Rustin GJ. The role of low-dose methotrexate and folinic acid in gestational trophoblastic tumours (GTT). Br J Obstet Gynaecol. 1989 Jul;96(7):795-802. doi: 10.1111/j.1471-0528.1989.tb03318.x. |
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| 15170794 | Background | Elson J, Tailor A, Banerjee S, Salim R, Hillaby K, Jurkovic D. Expectant management of tubal ectopic pregnancy: prediction of successful outcome using decision tree analysis. Ultrasound Obstet Gynecol. 2004 Jun;23(6):552-6. doi: 10.1002/uog.1061. |