Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Due to the difficulty in following pregnant women due to the covid 19 pandemic
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
During pregnancy many physiological changes and adaptations occur.Hormonal, hematological and hemodynamic changes are responsible for most of the ocular adaptations.We are planning to compare the choroid and retinal blood flow values and choroidal thickness of pregnant women and healthy non pregnant women with optical coherence tomography and optic coherence tomography angiography
During pregnancy many physiological changes and adaptations occur such as pulmonary, renal, endocrinological, haematological and visual system changes are happening. In previous studies, retinal and choroidal pregnancy-related changes in blood flow and choroidal thickness have been demonstrated. Optical coherence tomography angiography (OCTA) detects the contrast of motion in the blood flow, detecting the capillary of the retina and choroid.
It is a new functional method that visualizes the retinal networks and outer retina without using dyes.It is a non-invasive method that provides volumetric angiography information. In this study evaluation of the variability of choroidal and retinal blood flow changes and choroidal thickness, between trimesters of pregnancy and the non-pregnant control group is planned. Choroid and Retinal Blood Flow Values and Choroidal thickness in 41 pregnant women in the first trimester and it would be repeated at second and third trimesters. We compare measured values between trimesters and 45 healthy non-pregnant women.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pregnant Women | Healty pregnant women between 18-45 years,with no history of eye surgery and systemical disease.In 1st , 2nd and 3rd trimesters the measurements will be repeated |
| |
| Control Group | Healty non-pregnant women between 18-45 years with no history of eye surgery and systemical disease. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Optical Coherence Tomography,Optical Coherence Tomography Angiography(Topcon) | Diagnostic Test | Optical coherence tomography optical coherence tomography angiography |
|
| Measure | Description | Time Frame |
|---|---|---|
| Choroidal thickness | Choroidal thickness is measured by optical coherence tomography | 40 weeks |
| Retinal thickness | Retinal thickness is measured by optical coherence tomography | 40 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Foveal avascular zone(FAZ) area measurement | FAZ area is measured by optical coherence tomography anjiography | 40 weeks |
| Retinal vascular density | % of retinal vascular density is measured by optical coherence tomography angiography |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Retinal and choroid thickness and retinal angiographic values will be measured in healthy pregnant population (1 time for each trimester,totally 3 times) and healty control group
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Akdeniz University Hospital | Antalya | 07070 | Turkey (Türkiye) |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| 40 weeks |
| Retinal nerve fiber layer thickness | Retinal nerve fiber layer thickness (um) is measured by optical coherence tomography | 40 weeks |
| Ganglion cell layer measurement | Ganglion cell layer measurement is measured by optical coherence tomography | 40 weeks |
| ID | Term |
|---|---|
| D041623 | Tomography, Optical Coherence |
| D063171 | Corneal Pachymetry |
| D014065 | Tonometry, Ocular |
| D001795 | Blood Pressure Determination |
| ID | Term |
|---|---|
| D041622 | Tomography, Optical |
| D061848 | Optical Imaging |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D014054 | Tomography |
| D008919 | Investigative Techniques |
| D003941 | Diagnostic Techniques, Ophthalmological |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D010808 | Physical Examination |
Not provided
Not provided