Influence of Postoperative Cognitive Function in Patients With Sevoflurane Postconditioning on Carotid Intima Stripped

The Influence of Postoperative Cognitive Function in Patients With Sevoflurane Postconditioning on Carotid Intima Stripped

Brief summary: In order to get a better clinical plan for brain protection during perioperative anesthesia for high-risk patients - carotid intima stripped. We observing the hemodynamic changes of sevoflurane post-treatment in carotid intima stripped, the comparison of postoperative cognitive function and postoperative radiographic changes.

Inclusion Criteria:

• American Society of Anesthesiologists（ASA）：II-III
• Aged between 40 and 80 years
• Patients scheduled for surgery of Carotid stenosis under general anaesthesia

Exclusion Criteria:

• Has a history of mental illness can't cooperate,
• Serious heart block or cardiac decompensation or severe sinus slow (HR < 50 times/min),
• The abnormal nerve monitoring in operation, MMES preoperative score < 20 points,
• Any rescue unexpected occurred during the operation