Intensive Combination Approach to Rollback the Epidemic in Nigerian Adolescents: UH3 Phase

Intensive Combination Approach to Rollback the Epidemic in Nigerian Adolescents: UH3 Phase

Combination interventions with mHealth and Peer Navigation components will be evaluated in a randomized, stepped wedge trial among youth in Ibadan, Lagos, Sagamu, and Jos, Nigeria. Study findings will demonstrate whether or not the combination interventions for HIV treatment outcomes, which were found to be efficacious in our prior pilot UG3 trial, will remain efficacious if scaled as proposed in this UH3 trial, across multiple sites.

A randomized stepped wedge (cluster) trial will be conducted to investigate a combination interventions (with mHealth + Peer Navigation components) among youth in Ibadan, Lagos, Sagamu, and Jos, Nigeria. The Treatment Intervention will test a combination intervention that targets HIV treatment outcomes (retention, adherence and viral suppression).

Inclusion Criteria:

• Living with HIV infection
• Registered in the study clinics or their satellite clinics
• On antiretroviral therapy (ART) for at least 3 months
• Intention to remain a study clinic patient during the study observation and intervention period

Exclusion Criteria:

• Inability to provide informed consent
• Youths who are 15 years old and not emancipated, who do not have parental consent