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| Name | Class |
|---|---|
| Tartu University Hospital | OTHER |
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Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial therapy after surgery in complicated appendicitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 24 hour intravenous antibacterial therapy | Active Comparator | S.Augmentin 1,2g x 3 i/v |
|
| 24 hour oral antibacterial therapy | Experimental | T.Augmentin 1g x 3 p/o |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oral versus intravenous administration of antibacterial treatment | Other | Mode of administration of antibacterial treatment |
|
| Measure | Description | Time Frame |
|---|---|---|
| Infectious complications | 30 days |
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Inclusion Criteria:
Patients diagnosed with acute appendicitis and are candidates for laparoscopic appendectomy.
Exclusion Criteria:
Patients with compromised immune system (HIV, diabetes), ongoing or completed radio-chemotherapy in past 5 years, prosthetic heart valve, vascular prosthesis, pregnancy.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Edgar Lipping, MD | Contact | 6171520 | edgar.lipping@regionaalhaigla.ee | |
| Sten Saar, MD, PhD | Contact | 6171520 | sten.saar@regionaalhaigla.ee |
| Name | Affiliation | Role |
|---|---|---|
| Edgar Lipping, MD | North Estonia Medical Centre | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| North Estonia Medical Centre | Recruiting | Tallinn | Estonia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37747168 | Derived | Lipping E, Saar S, Reinsoo A, Bahhir A, Kirsimagi U, Lepner U, Talving P. Short Postoperative Intravenous Versus Oral Antibacterial Therapy in Complicated Acute Appendicitis: A Pilot Noninferiority Randomized Trial. Ann Surg. 2024 Feb 1;279(2):191-195. doi: 10.1097/SLA.0000000000006103. Epub 2023 Sep 25. |
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RCT
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| ID | Term |
|---|---|
| D001064 | Appendicitis |
| ID | Term |
|---|---|
| D059413 | Intraabdominal Infections |
| D007239 | Infections |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D002429 | Cecal Diseases |
| D007410 | Intestinal Diseases |
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