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| Name | Class |
|---|---|
| Citruslabs | INDUSTRY |
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A randomized-controlled interventional clinical trial to evaluate the effectiveness of EZC Pak & EZC Pak+D for the treatment of the common cold and/or a URI.
This is a randomized-controlled interventional treatment study with three arms of comparable demographics to evaluate the efficacy of PPC Pharmaceuticals EZC Pak (& EZC Pak+D) to improve the severity and duration of the common cold or a URI in individuals. It is hypothesized that study participants will experience a positive impact on the duration and severity of their cold/URI while using EZC Pak (&EZC Pak+D). The second study objective is to examine if patients are accepting the test product as an alternative to antibiotics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention 1 | Active Comparator | EZC Pak |
|
| Intervention 2 | Active Comparator | EZC Pak+D |
|
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EZC Pak | Dietary Supplement | After the onset of common cold symptoms, participants will take one pill (EZC Pak) each day for a period of 5 days. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Primary Objective: Reduction in severity of common cold symptoms | The primary objective of this study is to understand if EZC Pak (and EZC Pak +D) changes the severity and duration of an upper respiratory illness (URI) compared to a placebo. The study uses a scale of 1-4 (no symptoms to severe symptoms) to assess the effectiveness of the intervention. | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
Unwilling to try the test product for their cold
Has any of the following medical conditions:
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| Name | Affiliation | Role |
|---|---|---|
| Susanne Mitschke, BSc, MSc | Citruslabs | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Citruslabs | Santa Monica | California | 90404 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37163146 | Derived | Radhakrishnan A, Spencer S, Yanamala N, Malepati S. Evaluating the Efficacy and Safety of EZC Pak, a 5-Day Combination Echinacea-Zinc-Vitamin C Dose Pack with or without Vitamin D, in the Management of Outpatient Upper Respiratory Infections. Infect Drug Resist. 2023 May 3;16:2561-2572. doi: 10.2147/IDR.S392087. eCollection 2023. |
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| ID | Term |
|---|---|
| D003139 | Common Cold |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D010850 | Picornaviridae Infections |
| D012327 | RNA Virus Infections |
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| EZC Pak +D | Dietary Supplement | After the onset of common cold symptoms, participants will take one pill (EZC Pak +D) each day for a period of 5 days. |
|
| Placebo | Dietary Supplement | After the onset of common cold symptoms, participants will take one pill (Placebo) each day for a period of 5 days. |
|
| D014777 |
| Virus Diseases |
| D012140 | Respiratory Tract Diseases |