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The aim is to evaluate and compare treatment strategies for non-muscle invasive bladder cancer. Furthermore, the impact of intravesical instillations on bladder function will be examined by urodynamic examination both prior to and following instillation therapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TURBT alone | Patients treated with TURBT without adjuvant instillation therapy |
| |
| TURBT and mitomycin C | Patients treated with TURBT followed by six adjuvant instillations with mitomycin C |
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| TURBT and bacillus Calmette-Guerin | Patients treated with TURBT followed by six adjuvant instillations with BCG |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Urodynamic examination | Other | A urodynamic examination is performed in all patients four to six weeks following TURBT and repeated six months later in order to obtain bladder function and possible changes. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in urodynamic specifics (bladder compliance, detrusor overactivity, maximal cystometric capacity) | Obtained from the urodynamic test | examined at time 0 and after six months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients diagnosed with primary non-muscle invasive bladder cancer or who are diagnosed with their first or second recurrence.
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| Name | Affiliation | Role |
|---|---|---|
| Jørgen B. Jensen, DMSc, MD | Aarhus University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aarhus University Hospital | Aarhus | 8200 | Denmark |
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| ID | Term |
|---|---|
| D000093284 | Non-Muscle Invasive Bladder Neoplasms |
| ID | Term |
|---|---|
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| D001749 |
| Urinary Bladder Neoplasms |
| D014571 | Urologic Neoplasms |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D001745 | Urinary Bladder Diseases |
| D014570 | Urologic Diseases |
| D052801 | Male Urogenital Diseases |