• Collaborative Model of Care Between Orthopaedics and Allied Healthcare Professionals Trial (CONnACT)

  NCT03809975

  Unknown statusInterventionalNot ApplicableUpdated Oct 8, 2021
• Cohort of Lower-Extremity Sports Injuries and Degeneration(Yongjiang Cohort)

  NCT07592871

  RecruitingObservationalUpdated Aug 17, 2026
• A Multi-Center Bidirectional Cohort Study on Total Knee Arthroplasty for the Treatment of Knee Osteoarthritis

  NCT06990594

  Not yet recruitingObservationalUpdated May 25, 2025
• Traditional Chinese and Western Medicine for Knee Osteoarthritis

  NCT05133934

  Unknown statusObservationalUpdated Nov 24, 2021
• Responsiveness and Minimal Clinically Important Difference (MCID) of Knee Injury and Osteoarthritis (KOOS-12) in (OA)

  NCT06901921

  Active, not recruitingObservationalUpdated Mar 30, 2025
• Biomechanics and Clinical Outcomes in Responders and Non-Responders

  NCT06080763

  Unknown statusObservationalUpdated Mar 15, 2024

ClinicalTrials.gov ID

NCT04942236

Lead Sponsor

Tan Tock Seng HospitalOTHER

Overall Status

Unknown status

Study Type

Observational

Enrollment

500Estimated

Last Update Posted

Jun 28, 2021Actual

Start Date

Jun 30, 2021Estimated

Primary Completion Date

Dec 31, 2023Estimated

Completion Date

Dec 31, 2024Estimated

Official Title

Collaborative Model of Care Between Orthopaedics and Allied Health Care Professionals (CONNACT) OA Knee Cohort

Brief Summary

CONNACT OA knee cohort is a prospective longitudinal cohort study where we aim to collect sociodemographic, psychosocial, clinical, health utilization and cost data in order to better understand the Asian OA knee cohort and investigate for prognostic variables that can potentially influence a patients clinical outcome and treatment decisions.

In addition, the CONNACT OA knee cohort will form the basis for a cohort multiple randomized control trial (cmRCT) study design where multiple interventions can be tested in a randomized fashion. Each intervention is offered to a randomly selected sample of patients eligible for that intervention, who are then compared with the rest of the eligible patients from the cohort that are still being treated as usual.

• Osteoarthritis, Knee

Ages Eligible for Study

Adult (18-64)Older Adult (65+)

Sexes Eligible for Study

All

Accepts Healthy Volunteers

No

Eligibility Criteria

Inclusion Criteria:

1. Knee Osteoarthritis (based on NICE guidelines)
2. Age > 45 years
3. Community ambulator with or without walking aid
4. Conversant in English or Chinese

Exclusion Criteria:

1. Alternative diagnosis to Knee OA e.g. referred pain from spine or hip
2. Other forms of knee arthritis e.g. inflammatory, post-traumatic
3. Moderate to severe cognitive impairment e.g. dementia
4. Previous knee arthroplasty
5. Wheelchair bound patients
6. Medical conditions that will medically interfere with rehabilitation involvement e.g. decompensated heart failure, stroke with significant deficit, end stage renal failure

Observational Model

Cohort

Time Perspective

Prospective

Lead Sponsor

Tan Tock Seng HospitalOTHER

Collaborators

National Healthcare Group, SingaporeOTHER_GOV

Khoo Teck Puat HospitalOTHER

Woodlands Health CampusOTHER_GOV

bryan_tan@whc.sg63577713