The primary goal is to detect Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV2) urine viral particles in patients in intensive care units, hospitalized for coronavirus Coronavirus Disease-19 (COVID-19) infection, and correlate the presence of the virus in the urine with proximal tubular dysfunction (defined by the association of at least 2 abnormalities: tubular proteinuria, renal phosphate leak, uricosuria, normoglycemic glycosuria, amino aciduria)

Inclusion Criteria:

• Person and / or trustworthy person who has received complete information on the organization of the research and who has not opposed their participation and the use of their data
• Hospitalized for ≥ 48 hours and ≤ 10 days
• SARS-CoV-2 positive nasopharyngeal sample
• Severity criteria: Lung involvement described as compatible with SARS-CoV-2 on radiography or scanner and partial pressure of oxygne (PaO2) / Fraction of inspired oxygen (FiO2) ≤ 300 mmHg and / or respiratory rate (RR) ≥ 30 / min

Exclusion Criteria:

• Known chronic kidney disease, or initial Glomerular Filtration Rate (GFR) <60 ml / min / 1.73m2 or Renal Transplant
• Known proteinuria
• Known proximal tubulopathy
• Treatment with Forxiga

Patients hospitalized in CHRU Nancy with severe SARS-CoV2 infection, with lung involvement.