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| Name | Class |
|---|---|
| University Hospital of Berlin | OTHER |
| University Hospital of Cologne | OTHER |
| University Hospital Freiburg | OTHER |
| University of Giessen |
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Survey on the prevalence of MDRO to monitor the import of MDRO from the community. Rectal swabs will be taken and cultivated. Survey on community-onset and nosocomial bloodstream infections will be documented and strains will be isolated. For each BSI a clinical data set will be obtained (e.g. patient age, gender, date of hospitalization, antibiotic therapy). Genetic analysis of MDRO from the prevalence and BSI study. In a subset of patients the microbiome-resistome interactome will be analysed in more detail. Furthermore, the impact of infection control measures due to the Covid-19 pandemic on nosocomial BSI will be investigated.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| rectal swab | Other | collection of rectal swabs |
| Measure | Description | Time Frame |
|---|---|---|
| monitoring of MDRO prevalence | obtain a better understanding for the emergence of resistance within the microenvironment under selective pressure | at hospital admission |
| monitoring of blood stream infections | obtain a better understanding for the emergence of resistance within the microenvironment under selective pressure | during hospitalization, up to 4 weeks |
| integrate novel techniques for microbiome-resistome interaction analysis | obtain a better understanding for the emergence of resistance within the microenvironment under selective pressure | through study completion, after 4 years |
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Inclusion Criteria:
Exclusion Criteria:
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For the prevalence, adult patients admitted to the hosptial within the last 3 days.
For BSI surveillance, adult inpatients with at least one blood culture positive for any of the target organisms: Staphylococcus aureus, Enterococcus spp., Escherichia coli, Enterobacter spp., Klebsiella spp., Acinetobacter baumannii, Pseudomonas aeruginosa.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Klinik für Infektiologie und Mikrobiologie | Lübeck | Germany |
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| OTHER |
| University Hospital Tuebingen | OTHER |
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Bacterial strains isolated from rectal swabs, blood cultures and samples derived thereof (such as purified DNA)