Monitoring of MDRO Dynamics and Resistance Mechanisms in a University Hospital Network

Monitoring of MDRO Dynamics and Resistance Mechanisms in a University Hospital Network

Survey on the prevalence of MDRO to monitor the import of MDRO from the community. Rectal swabs will be taken and cultivated. Survey on community-onset and nosocomial bloodstream infections will be documented and strains will be isolated. For each BSI a clinical data set will be obtained (e.g. patient age, gender, date of hospitalization, antibiotic therapy). Genetic analysis of MDRO from the prevalence and BSI study. In a subset of patients the microbiome-resistome interactome will be analysed in more detail. Furthermore, the impact of infection control measures due to the Covid-19 pandemic on nosocomial BSI will be investigated.

Inclusion Criteria:

• at least 18 years old
• informed consent
• inpatient

Exclusion Criteria:

• less than 18 years old
• Not capable of giving informed consent
• outpatient