Clinical data of 185 consecutive patients receiving resective operation with a pathological diagnosis of craniopharyngioma in our hospital between January 2013 and February 2021 were collected. Among these patients, 18 of them were recognized as craniopharyngioma with tumoral hemorrhage during the operation.

For each case, age, gender, smoking status, alcohol intake, past history, symptoms, blood pressure, blood cell count, blood biochemical tests, coagulation tests, hormone tests, radiological results, surgical treatment and the outcome at discharge were collected. The first test result after admission and before the operation was taken for the items of blood tests with multiple times in the analysis.

Inclusion Criteria:

• receive resective operation with a pathological diagnosis of craniopharyngioma in our hospital
• enter our hospital between January 2013 and February 2021

Exclusion Criteria:

• have a non-craniopharyngioma or unverified pathological diagnosis at discharge
• have received surgical or radiological treatment on the sellar region
• receive treatment of coagulation modulation, immunosuppressive agents or chemotherapeutic drugs
• combine with other clinical emergencies including acute myocardial infarction, cerebral stroke, trauma and sepsis at admission
• have been diagnosed with other tumors, hematological diseases, autoimmune diseases, liver failure or renal failure

patients with a pathological diagnosis of craniopharyngioma

Due to the sensitive nature of the questions asked in this study, survey respondents were assured raw data would remain confidential and would not be shared.