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| Name | Class |
|---|---|
| King's College Hospital NHS Trust | OTHER |
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To non-invasively estimate the alveolar surface area of the lungs of prematurely born infants by taking measurements of oxygen and carbon dioxide and utilizing functional morphometry.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Assessment of alveolar surface area by functional morphometry | Experimental | Non-invasive measurements of V/Q |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Calculation of ventilation-perfusion ratio | Other | Three to five paired measurements of fraction of inspired oxygen and peripheral oxygen saturations. Insertion of mainstream capnograph with combined pressure and flow sensor to perform end-tidal capnography measurement. Echocardiogram to assess intra-cardiac shunting. |
| Measure | Description | Time Frame |
|---|---|---|
| Calculation of the alveolar surface area in prematurely born infants using validated functional morphometry | One year |
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Inclusion Criteria:
-
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Anne Greenough | King's College London | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| King's College Hospital NHS Foundation Trust | London | United Kingdom |
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| ID | Term |
|---|---|
| D001997 | Bronchopulmonary Dysplasia |
| ID | Term |
|---|---|
| D055397 | Ventilator-Induced Lung Injury |
| D055370 | Lung Injury |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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|
| D007235 |
| Infant, Premature, Diseases |
| D007232 | Infant, Newborn, Diseases |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |