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As the secondary choice of artery grafts, radial artery is more and more used to achieve multiple arterial revascularization in CABG. Risk factors for predictors of major cardiovascular adverse events (MACE) after CABG using radial-artery grafts (RA-CABG), however, remain uncertain. This case-control study aims to identify the baseline predictors of MACE after RA-CABG.
We will collect the baseline characteristics and perioperative data of patients underwent RA-CABG from Jan. 2009 to Dec. 2019 in our single center. By reviewing the latest follow-up records, we will examine the correlation between the baseline characteristics and clinical outcomes (MACEs), then identify the independent risk factors for predictors of MACEs after RA-CABG.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MACE Group | MACE Group includes the patients suffered from any component of MACE after RA-CABG until the latest follow-up. | ||
| Non-MACE Group | Non-MACE Group includes the patients freed from any component of MACE after RA-CABG until the latest follow-up. |
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| Measure | Description | Time Frame |
|---|---|---|
| 7-day MACE-4 | a composite of all-cause death, myocardial infraction, stroke and repeat revascularization | 7 days post-CABG |
| 30-day MACE-4 | a composite of all-cause death, myocardial infraction, stroke and repeat revascularization | 30 days post-CABG |
| 1-year MACE-4 | a composite of all-cause death, myocardial infraction, stroke and repeat revascularization | 1 year post-CABG |
| 3-year MACE-4 | a composite of all-cause death, myocardial infraction, stroke and repeat revascularization | 3 years post-CABG |
| Measure | Description | Time Frame |
|---|---|---|
| MACE-3 | a composite of CV-death, myocardial infraction and stroke | 7 days, 30 days, 1 year, and 3 years post-CABG |
| All-cause death | Death from any cause |
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Inclusion Criteria:
Exclusion Criteria:
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Patients 18-year and above underwent RA-CABG from Jan. 2009 to Dec.2019 in one single center.
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| Name | Affiliation | Role |
|---|---|---|
| Qiang Zhao, MD | Ruijin Hospital | Principal Investigator |
| Yunpeng Zhu, MD | Ruijin Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ruijin Hospital Shanghai Jiao Tong University School of Medicine | Shanghai | Shanghai Municipality | 200025 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37829689 | Result | Xia T, Li B, Zhang W, Wang Z, Ye X, Zhou M, Li H, Qiu J, Zhu Y, Zhao Q. Risk factors for major adverse cardiovascular events after coronary artery bypass grafting using radial artery grafts. Front Cardiovasc Med. 2023 Sep 27;10:1238161. doi: 10.3389/fcvm.2023.1238161. eCollection 2023. |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| 7 days, 30 days, 1 year, and 3 years post-CABG |
| CV-death | Including death resulting from an acute myocardial infarction , sudden cardiac death, death due to heart failure, death due to stroke, death due to cardiovascular procedures, death due to cardiovascular hemorrhage, and death due to other cardiovascular causes | 7 days, 30 days, 1 year, and 3 years post-CABG |
| Myocardial infraction | According to the 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials, including CABG-related MI, non CABG-related MI, silent MI and unknown type. | 7 days, 30 days, 1 year, and 3 years post-CABG |
| Stroke | According to the 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials, including ischemic, hemorrhagic and unknown type. | 7 days, 30 days, 1 year, and 3 years post-CABG |
| Repeat revascularization | According to the 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials, including any PCI and CABG. | 7 days, 30 days, 1 year, and 3 years post-CABG |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |