Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| National Institute on Disability, Independent Living, and Rehabilitation Research | FED |
| University of California, Los Angeles | OTHER |
Not provided
Not provided
Not provided
Not provided
Study is a randomized clinical trial evaluating the efficacy of novel mobile application technologies (including Seeing AI, Aira, and Supervision+) to improve quality of life in older adults with low vision by expanding community access and providing assistance with activities of daily living. Aira provides real-time remote personal assistance through a sighted Aira agent supplying direct feedback to assist with visual tasks. Seeing AI provides optical character recognition allowing any text to be read aloud, color identification, bar code reading, scene description, and facial recognition based on stored photos. Supervision + allows one to use the phone as a magnifier, providing magnification and contrast enhancement using the camera of the mobile phone. This study seeks to understand the potential of these technologies to improve daily activities, community participation, independence, and self-sufficiency in this group by examining a technological approach, which has not yet undergone rigorous investigation in a diverse population of older adults with visual impairment. Project objectives are to evaluate mobile applications in a wide range of visual disability, categorized into three groups: (1) mild to moderate visual acuity loss, (2) severe to profound visual acuity loss, and (3) legal blindness secondary to visual field loss. Participants are randomized to one of three intervention groups: (1) Supervision+ application, (2) Aira application, or (3) Seeing AI application for a period of 6 months. For the Aira intervention group, participants will be assigned either with 'restricted' access (current open access areas plus 30 minutes/month anywhere), or 'unrestricted' access (700 minutes), for a period of 3 months with a 3 month cross-over period. Participants may elect to continue the study for an additional 3 months during which time they have access to all 3 study mobile applications. Outcome measures include assessment of changes at three, six and nine months post-intervention for: visual ability, health state (including depression), self-efficacy, loneliness, life space, distances travelled from the home, and types of services obtained.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Seeing AI Smart Phone App | Experimental | Intervention: Behavioral: Low Vision Rehabilitation |
|
| Supervision+ Smart Phone App | Experimental | Intervention: Behavioral: Low Vision Rehabilitation |
|
| Aira Smart Phone App | Experimental | Intervention: Behavioral: Low Vision Rehabilitation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low Vision Rehabilitation | Behavioral | Smart phone App |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual ability change score | The primary outcome measure is the person change score (before and after intervention), from the adaptive Massof Activity Inventory (AI) Questionnaire. The AI has an item bank of 510 items organized into 50 goals and 460 related visually-based tasks. Subscales range from 0 (not important) to 3 (very important). For those goals rated as important, subjects are asked to rate the task difficulty on subscales of 0 (impossible to do without help) to 5 (not difficult). Rasch analysis is employed to estimate visual ability from these difficulty ratings, on an interval scale. With Rasch analysis person measures are estimated, whereby a more positive person measure reflects greater visual ability. In this study, we will explore the the difference in person measures (i.e. change score) after the intervention at 3 and 6 months. A larger, more positive change score indicates greater visual ability since intervention. | AI questionnaire will be administered three times over 6 months: baseline, 3-months post-intervention and 6-months post-intervention, and also 9 months post-intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Health-related Quality of Life: SF-36 | questionnaire; scale ranges from 1 (excellent) to 5 (poor), with higher values indicating greater difficulty. | will be administered three times over 6 months: baseline, 3-months post-intervention and 6-months post-intervention and also 9 months post-intervention |
| Beck Depression Inventory |
| Measure | Description | Time Frame |
|---|---|---|
| Telephone Interview of Cognitive Status (TICS) | questionnaire; with subscales 0 to 1, with higher scores indicating greater cognitive ability. | administered at time of enrollment |
| Psychosocial Impact of Assistive Devices Scale (PIADS) |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UCLA Stein Eye Institute | Los Angeles | California | 90095 | United States | ||
| New England College of Optometry |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39443965 | Derived | Gobeille M, Bittner AK, Malkin AG, Ho J, Idman-Rait C, Estabrook M, Ross NC; CARE Study Team. Rasch analysis of the new general self efficacy scale: an evaluation of its psychometric properties in older adults with low vision. Health Qual Life Outcomes. 2024 Oct 23;22(1):90. doi: 10.1186/s12955-024-02306-2. | |
| 38990234 | Derived |
Not provided
Not provided
Data will be shared according to the protocols stipulated by NIDILRR and the IRB at NECO and UCLA.
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D015354 | Vision, Low |
| ID | Term |
|---|---|
| D014786 | Vision Disorders |
| D012678 | Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
questionnaire; subscales range from 0 to 3, with higher values indicating greater depression. |
| will be administered three times over 6 months: baseline, 3-months post-intervention and 6-months post-intervention and also 9 months post-intervention |
| Community Living: Life Space Questionnaire | questionnaire; subscales range from 1 (Yes) to 2 (No), with a higher total value indicating a more restricted life space. | will be administered three times over 6 months: baseline, 3-months post-intervention and 6-months post-intervention and also 9 months post-intervention |
| 3-item UCLA Loneliness Scale | questionnaire; subscales range from 1 to 3, with a high value indicating increased loneliness. | will be administered three times over 6 months: baseline, 3-months post-intervention and 6-months post-intervention and also 9 months post-intervention |
| New General Self Efficacy Scale | questionnaire; subscales range from 1 to 5, with a higher value indicating greater self-efficacy. | will be administered three times over 6 months: baseline, 3-months post-intervention and 6-months post-intervention and also 9 months post-intervention |
| App usage frequency | App usage in minutes. | at 3 months post-intervention and 6 months post intervention and also 9 months post-intervention |
questionnaire; with subscales from -3 to 3, higher scores indicate greater affinity of a particular factor to assistive technology use.
| administered at 3-months post-intervention and 6-months post-intervention and also 9 months post-intervention |
| Aira Explorer Survey post intervention feedback | (specific to those participants randomized to Aira); questionnaire, with subscales ranging from 0 to 10, higher scores indicate stronger agreement or helpfulness of the Aira App. | 6 months and also 9 months post-intervention |
| Boston |
| Massachusetts |
| 02115 |
| United States |
| Bittner AK, Gobeille M, Malkin AG, Ho J, Idman-Rait C, Estabrook M, Ross NC; CARE Study Team. Life space limitations in visually impaired older adults. Optom Vis Sci. 2024 Jun 1;101(6):321-328. doi: 10.1097/OPX.0000000000002150. |
| 38820379 | Derived | Malkin AG, Bittner AK, Ho J, Idman-Rait C, Estabrook M, Ross NC; CARE Study Team. Factors related to training time and achieving proficiency with visual-assistive mobile applications in visually impaired older adults. Optom Vis Sci. 2024 Jun 1;101(6):351-357. doi: 10.1097/OPX.0000000000002135. Epub 2024 May 31. |
| D005128 |
| Eye Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |