Despite the global preventive efforts (physical distancing, face, mask, travel constraints, and quarantine) to contain the infection, COVID-19 is continuing with its devastating consequences on health, life, and economics. The world's hopes are attached to a successful preventive measure that is the vaccination which has proved its capability to stop infections and save lives over the years. World Health Organization (WHO) declared vaccination hesitancy as one of the top 10 obstacles for global health. Multicentric study involved Arab countries measure hesitancy of HCWs toward vaccine, it reported the highest rates of hesitancy were among participants from the western regions of the Arab world (Egypt, Morocco, Tunisia, and Algeria). This study aims to evaluate the attitude and the determinants of this attitude of HCWs towards receiving or refusing to have their first dose of vaccination.

Inclusion Criteria:

• All staff how are working in AUH and offered to receive the first dose of AstraZeneca & Sino pharm vaccine.

Exclusion Criteria:

• Those who are not eligible to receive the vaccine
• Those who are not freely offered to receive the vaccine

All healthcare workers in Assiut university hospitals how are eligible for COVID-19 vaccination and the vaccine is freely offered to them