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The main aim of the present study is to investigate whether mimicking emotional expressions training via FaceReader software can improve emotional processing and recognition in healthy subjects, especially individuals with hityer autistic traits.
Some mood and trait questionnaires such as Autism Spectrum Quotient, Social Responsiveness Scale,State-Trait Anxiety Inventory,Beck's Depression Inventory etc are asked to complete. 90 healthy male subjects will receive 16 times (4 times a week , 4 weeks) of mimicking emotional expressions training via Facereader. During training, 3 times of fNIRS (t2,t9 and t16) were recorded simultaneously. fMRI scanning, including emotion processing and emotion recognition tasks, 7 minutes resting data, ans DTI data will be collected before and after the training. After fMRI scaning, behavioral ratings (i.e. intensity and valence) and eye-tracking data will be collected.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lower austic sub-group | Active Comparator | 16 times of mimicking emotional expressions |
|
| Higher austic sub-group | Experimental | 16 times of mimicking emotional expressions |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mimic facial expressions | Behavioral | 16 times (4 times a week, last 4 weeks) of mimicking facial expressions. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intensity score of subjects' mimic facial emotions | The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into intensity, ranging from 0 to 1. | an average of 4 weeks |
| Valence score of subjects' mimic facial emotions | The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into valence, ranging from -1 to 1. | an average of 4 weeks |
| Arousal score of subjects' mimic facial emotions | The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into arousal, ranging from 0 to 1. | an average of 4 weeks |
| Task-dependent functional MRI data | Neural activities of brain regions, notably mirror neuron system will be collected for analysis when the subjects participate in a face processing and emotion recognition task in a MRI scanner before and after the 4-week training session. | an average of 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Keith Kendrick, Dr. | Contact | 86-28-61830811 | k.kendrick.uestc@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Weihua Zhao, Dr. | University of Electronic Science and Technology of China | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Electronic Science and Technology of China | Recruiting | Chengdu | Sichuan | 611731 | China |
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