Community-based Post-exposure Prophylaxis for COVID-19

Community-based Post-exposure Prophylaxis for COVID-19: Results and Implications of Ayurveda Practice Guidelines

Specifically identified Ayurvedic preparations is recommended by ministry of AYUSH as post-exposure prophylaxis to efficaciously prevent a negative person who has come into contact with COVID-19-positive. Traditionally, recommended Ayurvedic preparations have been used as antioxidants, antimicrobial and anti-inflammatory properties. Particularly, Guduchi Ghanvati has been recognised with its ability to control viral attachment, viral replication and induce immune response in pre clinical settings, and found to be one among the most important drugs in Ayurveda to fight against COVID-19.

However, known gap in guideline implementation and its impact on preventing active infection in exposed cases is unclear. Study aimed to increase the use of recommended AYUSH guidelines by having registered AYUSH physicians provide these medications, when indicated, in community based participants after known exposure to the SARS-CoV-2 coronavirus.

Inclusion Criteria:

• Men or women 18 to 60 years of age
• Household contact residing with the index case in the 14 days prior to index diagnosis within a residence without maintaining social distance
• Access to device and internet for telephonic appointments and follow up

Exclusion Criteria:

• Currently hospitalised
• Symptomatic with fever, cough, or shortness of breath
• Use of anti-malarial treatment or chemoprophylaxis
• Moderately or Severely ill for any co-morbid condition requiring medical assistance.
• Cognitive impairment