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| Name | Class |
|---|---|
| Media Rez | UNKNOWN |
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This study will aim to assess the acceptability, usability and efficacy of using state-of-the-art video game technology to increase HIV testing among adolescents and young adults (AYA) ages 13-24. AYA often lack awareness of their personal risk of contracting HIV and where to go for testing and care. This lack of awareness has contributed to poor uptake of HIV testing among AYA despite engagement in high risk behaviors. The goal of this project is to harness this strong motivation to play games to increase HIV testing. Previous games for behavior change have yielded early success for increasing target behaviors among their sample populations, yet research on increasing HIV testing among AYA through gaming has been limited. This intervention builds on prior formative work and is designed to offer AYA personally-tailored risk messages and supports their accessibility to HIV testing and prevention services through an innovative gaming approach that is sharable over social media with in-game rewards for sharing the game with peers. The specific aim of this study is to determine the efficacy of a life-simulation game in changing HIV testing, knowledge, and risk behaviors among AYA at risk for HIV.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mobile Game | Experimental | An enhanced life-simulation prototype of a playable interactive game to increase HIV testing, risk assessment tool, and HIV and pre-exposure prophylaxis (PrEP) locators embedded within the game. |
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| Mobile Application | Active Comparator | A mobile application that will include basic information on HIV basics (e.g., routes of transmission, data on the epidemiology of HIV among youth), prevention information on HIV testing and PrEP, as well as a link to the HIV risk estimator, and HIV testing and PrEP locators. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mobile Game | Other | An enhanced life-simulation prototype of a playable interactive game to increase HIV testing. |
|
| Measure | Description | Time Frame |
|---|---|---|
| HIV testing | Self-reported HIV testing in the past 6 months | prior 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Intent to test for HIV | Intent to test will be assessed using a validated 6-point Likert scale | baseline, 1, 3, 6 months |
| HIV knowledge | 18-item scale |
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Inclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| George Washington University Milken School of Public Health | Washington D.C. | District of Columbia | 20052 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34185022 | Background | Castel AD, Wilbourn B, Trexler C, D'Angelo LD, Greenberg D. A Digital Gaming Intervention to Improve HIV Testing for Adolescents and Young Adults: Protocol for Development and a Pilot Randomized Controlled Trial. JMIR Res Protoc. 2021 Jun 24;10(6):e29792. doi: 10.2196/29792. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jan 12, 2026 | |
| Reset | Jan 27, 2026 | |
| Release | Feb 3, 2026 | |
| Reset | Feb 17, 2026 | |
| Release | Jun 12, 2026 | |
| Reset | Jul 8, 2026 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jan 12, 2026 | Jan 27, 2026 | |||
| Feb 3, 2026 |
| ID | Term |
|---|---|
| D000163 | Acquired Immunodeficiency Syndrome |
| ID | Term |
|---|---|
| D015658 | HIV Infections |
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
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| Mobile Application | Other | A mobile application that will include basic information on HIV basics (e.g., routes of transmission, data on the epidemiology of HIV among youth), prevention information, and information on HIV testing and PrEP, as well as a link to the HIV risk estimator, and HIV testing and PrEP locators. |
|
| baseline, 1, 3, 6 months |
| HIV risk perception and behaviors | 8-item scale and perceived likelihood of getting infected (0-100%) | baseline, 1, 3, 6 months |
| Knowledge of PrEP | Has participant heard of PrEP at specified time period | baseline, 1, 3, 6 months |
| CDC risk estimator scores | baseline, 1, 3, 6 months |
| Frequency of game use | 1, 3, 6 months |
| PrEP screening | ever been screened for PrEP eligibility | baseline, 1, 3, 6 months |
| PrEP use/uptake | been prescribed/taken PrEP | baseline, 1, 3, 6 months |
| PrEP locator use | Number of linkages to PrEP locator | baseline, 1, 3, 6 months |
| Duration of game use | 1, 3, 6 months |
| Reasons for continued or discontinued use of game | 1, 3, 6 months |
| HIV locator use | Number of linkage to HIV testing locator | baseline, 1, 3, 6 months |
| Feb 17, 2026 |
| Jun 12, 2026 | Jul 8, 2026 |
| D015229 |
| Sexually Transmitted Diseases, Viral |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012897 | Slow Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |