Refractive Transepithelial Photo-keratectomy (T-PKR) in High Myopia

Refractive Transepithelial Photo-keratectomy (T-PKR) Without Addition of Mitomycin-C in High Myopia: a Retrospective Study of 69 Eyes

The aim of this study is to evaluate the anatomical and refractive parameters following a single-step transepithelial photo-refractive keratectomy (T-PRK) without the addition of mitomycin-C for the treatment of high myopia of 6 diopters or more.

In this retrospective study, 69 high myopic eyes of 6 diopters or more were treated in 38 patients by Trans-PRK with the SCHWIND Amaris 500E® excimer laser platform without the use of mitomycin-C. Several outcomes are measured in treated patients, such as postoperative uncorrected visual acuity (UCVA), best spectacle corrected visual acuity (BSCVA), efficacy, safety and predictability of the procedure, as well as corneal haze measurement. The patients are followed-up for 3 months.

Inclusion Criteria:

• age ≥18 years,
• myopic sphere of -6 diopters or more,
• astigmatism less than 3 diopters,
• stable myopia not progressing for more than one year

Exclusion Criteria:

• age <18 years,
• myopic sphere less than -6 diopters,
• astigmatism greater than 3 diopters,
• progressive myopia (variation of more than 0.5 diopters over one year),
• abnormal corneal topography or the presence of manifest keratoconus,
• pre-existing eye pathology,
• history of eye surgery,
• active inflammatory or infectious eye disease,
• dermatological disease or systemic connectivitis