Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Hilfiker Roger | UNKNOWN |
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of this exploratory pilot study is to assess the feasibility and effectiveness of the adapted T&E home-based exercise program on the basic functional mobility and executive functions in persons with mild or probable Alzheimer's Disease.
Primary and secondary outcomes will be measured at T0 (one week before the begin of the intervention) and T1, (one week after the eight weeks of the intervention) at home of the participants.
Eight home-based physiotherapy sessions will occur in two months, once a week, to activate the preserved implicit memory (PIM). The recommendations are to train three weeks with the same exercise program, three times a week (one time coached by the attributed physiotherapist and two times coached by a natural or family caregiver). After three weeks, the participants can choose if they want to keep the same exercises or change all or some of these, in testing other tasks. Every training session will be planned to last 45 minutes. During each training session, the participant will note on his/her own "Training booklet" each task performed. The "Training booklet" will be used to plane, organize, and remember details for the next training session.
Twelve participants will take part at this study.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Test & Exercise home-based program (T&E) | Experimental | Eight home-based physiotherapy sessions will occur in two months, once a week |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Test and exercise home-based program | Other | Eight home-based physiotherapy sessions will occur in two months, once a week, to activate the preserved implicit memory (PIM). The recommendations are to train three weeks with the same exercise program, three times a week (one time coached by the attributed physiotherapist and two times coached by a natural or family caregiver). After three weeks, the participants can choose if they want to keep the same exercises or change all or some of these, in testing other tasks. Every training session will be planned to last 45 minutes. During each training session, the participant will note on his/her own "Training booklet" each task performed. The "Training booklet" will be used to plane, organize, and remember details for the next training session. |
| Measure | Description | Time Frame |
|---|---|---|
| Functional mobility | Berg Balance Scale (BBS), scoring ranges from 0 (worse) to 56 (best) | 8 weeks |
| Stand and go | Time Up and Go test (TUG) in seconds | 8 weeks |
| Sit to stand | Five Time Sit to Stand (FTSTS) in seconds | 8 weeks |
| Walking speed | The self-selected and the maximal walking speed (SSWS/MWS) on a 6-meter walk | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| The Set shifting (Mental flexibility) | Trail Making Test Part-Be in seconds | 8 weeks |
| The updating (Working memory) | Digit span backward task, number of the successful sequences between 0 and 14 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anne-Gabrielle Mittaz Hager, PhD Cand | Contact | 796099063 | 0041 | gaby.mittaz@hevs.ch |
| Roger Hilfiker, PhD Cand | Contact | 796883490 | 0041 | roger.hilfiker@hevs.ch |
| Name | Affiliation | Role |
|---|---|---|
| Anne-Gabrielle Mittaz Hager, PhD Cand | HES-SO Valais-Wallis | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CMS Sierre Région | Recruiting | Sierre | Valais | 3960 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38877608 | Derived | Carrard S, Eyer S, Hilfiker R, Mittaz Hager AG. Adapted Home-Based Exercises in Dementia: An Exploratory Pre-post Pilot and Feasibility Study. Am J Alzheimers Dis Other Demen. 2024 Jan-Dec;39:15333175241263741. doi: 10.1177/15333175241263741. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 5, 2024 | |
| Reset | Jul 17, 2024 |
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 5, 2024 | Jul 17, 2024 |
| ID | Term |
|---|---|
| D000544 | Alzheimer Disease |
| ID | Term |
|---|---|
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
|
| 8 weeks |
| The response inhibition | Stroop Color and Word Test (SCWT) Victoria, comparison of the expected score to the participant's score to calculate the Z-score | 8 weeks |
| Feasibility of recruitement | Inclusion of 12 subjects between the 30 of May 2021 ant the 30 of Septembre 2021 | 4 months |
| Participation agreement | Fulfilled if 75% of eligible subjects agree to participate and sign the consent | 4 months |
| Costs | Fulfilled if the cost does not exceed the planed amounts by more than 5% | 8 months |
| Drop out / withdraw | Fulfilled if 75% of the participants take part in the total duration of the study | 8 months |
| D024801 |
| Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |