Effect of Semaglutide 2.4 mg Once-weekly on Function and Symptoms in Subjects With Obesity-related Heart Failure With Preserved Ejection Fraction, and Type 2 Diabetes
Effect of Semaglutide 2.4 mg Once-weekly on Function and Symptoms in Subjects With Obesity-related Heart Failure With Preserved Ejection Fraction, and Type 2 Diabetes
This study will look at how participants' daily life is affected by their heart failure. The study will also look at the change in participants' body weight.
This study will compare the effect of semaglutide (a new medicine) compared to "dummy" medicine on body weight and heart failure symptoms.
Participants will either get semaglutide or "dummy" medicine, which treatment participants get is decided by chance.
Participants will need to take 1 injection once a week. The study medicine is injected with a thin needle in a skin fold in the stomach area, thigh or upper arm.
During the study participants will have talks with the study staff about healthy lifestyle and physical activity.
The study will last for about 59 weeks, that is a little more than 1 year. Participants will have 12 clinic visits with the study doctor.
Women cannot take part if pregnant, breast-feeding or plan to become pregnant during the study period.
Inclusion Criteria:
Exclusion Criteria:
CABA, Buenos Aires C1440CFD, Argentina
CABA, C1061AAS., Argentina
CABA, C1119ACN, Argentina
CABA, C1440CFD, Argentina
Ciudad Autónoma de Buenos Aire, 1425, Argentina
Ciudad Autónoma de Buenos Aire, 1425, Argentina
Rosario, Santa Fe, S2000CVB, Argentina
Saint Stefan, 8511, Austria
Berlin, 13353, Germany
New Delhi, National Capital Territory of Delhi 110002, India
New Delhi, National Capital Territory of Delhi 110062, India
New Dehli, New Delhi 110029, India
Okayama-shi, Okayama, 700-8558, Japan
Osaka-shi, Osaka, 530-8480, Japan
Bialystok, Podlaskie Voivodeship 15-276, Poland
Bialystok, Podlaskie Voivodeship 15-540, Poland
Gdynia, Pomeranian Voivodeship 81-157, Poland
Lodz, Łódź Voivodeship 90-549, Poland