Black Garlic Nutraceuticals and Blood Pressure Control

Black Garlic Nutraceuticals Supplementation for the Control of Blood Pressure in Hypertension. A Triple-blind Randomized Placebo Control Study.

Black garlic contains a series of allyl-sulfur compounds with the ability to modulate nitric oxide synthetase, angiotensin-converting enzyme system, and endothelial activation, which together could help better control blood pressure. The main objective of this study is to evaluate the effect on blood pressure and endothelial health of a daily intake of a black garlic supplement named ABG (registered mark), which has a higher concentration of black garlic bioactive compounds, in people with moderate hypertension.

Inclusion Criteria:

- Clinical hypertension, medically treated with no more than 2 drugs

Exclusion Criteria:

• Body mass index above 35 kg/m2
• Fasting blood cholesterol levels below 115 mg/dL
• Fasting blood glucose levels above 126 mg/dL
• Taking anyone of the Angiotensin-converting enzyme inhibitors
• Anemia (hemoglobin below 13 g/dL in men and below 12 g/dL in women)
• Vitamin or nutraceutical intake in the last 30 days before the study enrollment
• Chronic gastrointestinal diseases
• Pregnancy and breastfeeding
• Garlic allergy
• Participation in another study 30 days before the study enrollment