Assessment of the Impact of Gadolinium Injection on the Measurement of the QSM Signal

Assessment of the Impact of Gadolinium Injection on the Measurement of the QSM Signal

Patients meeting the inclusion and non-inclusion criteria will be offered to participate in the study. If they agree, they will perform an MRI without injection to obtain the QSM then perform the MRI with injection that was prescribed to them as part of the care, then they will perform a second time the MRI without injection to obtain the QSM. They will also answer a short questionnaire documenting their previous exposure to gadolinium.

Patients meeting the inclusion and non-inclusion criteria will be offered to participate in the study. If they agree, they will perform an MRI without injection to obtain the QSM then perform the MRI with injection that was prescribed to them as part of the care, then they will perform a second time the MRI without injection to obtain the QSM. They will also answer a short questionnaire documenting their previous exposure to gadolinium.

Inclusion Criteria:

• patients over 18 years old
• with an inflammatory CNS pathology
• to benefit as part of care from an MRI with injection of gadolinium
• consent to participate in the study
• beneficiary of a social protection scheme

Exclusion Criteria:

• pregnant or breastfeeding woman
• patient benefiting from a legal protection measure
• Patient having performed more than 3 MRI exams with gadolinium injection during his life

Secondary exclusion criteria :

• motion artifact not allowing image interpretation
• patient who has not completed one of the following sequences: T1 anatomical, FLAIR, or QSM pre-gadolinium injection.

Secondarily excluded patients will be replaced up to a maximum of 25 patients.