Resistance Training Effects on Gut Microbiome and Cardiometabolic Outcomes

Effects of 6-week Resistance Training Intervention on Gut Microbiome and Cardiometabolic Outcomes in Adults With Overweight and Obesity

The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.

The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.

Inclusion Criteria:

• Age 18-35 years
• BMI: 25-45 kg/m2
• Sedentary lifestyle
• Consistent diet patterns
• Weight-stable (<4 kg change over the last 3 mo)
• Willingness to adhere to resistance training protocol and not change diet
• Non-smoker >1 year or more

Exclusion Criteria:

• Disabilities preventing adherence to resistance training protocol
• Recent start of medications that affect metabolism or appetite
• Antibiotics
• Diabetes
• Drug therapy for coronary artery disease, peripheral artery disease, congestive heart failure, or dyslipidemia
• Uncontrolled hypertension and blood pressure ≥ 180/110
• Gastrointestinal disease and/or bariatric surgery
• Smoking
• Illicit drug use
• Pregnant or lactating individuals