Effect of Radiotherapy Concurrent of TTFields in Patients With Glioblastoma

The Clinical Effect and Safety of Radiotherapy Concurrent of TTFields in the Treatment of Post-operation Patients With Glioblastoma.

TTFields has been approved by the FDA for the treatment of patients with glioblastoma multiforme. However, the clinical effect and safety of radiotherapy concurrent of TTFields is not definite. In this study, the investigators conduct a phase II clinical trial to evaluate the efficacy and safety of this strategy.

the investigators plan to recruit 30 patients to evaluate the efficacy and safety of this strategy.

Inclusion Criteria:

• performance status of 0-1 (Eastern Cooperative Oncology Group performance status)
• histologically confirmed glioblastoma
• no cerebrospinal fluid and distant metastatic disease.

Exclusion Criteria:

• with a history of brain radiotherapy
• severe hepatic and renal dysfunction