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| Name | Class |
|---|---|
| University Hospital Birmingham | OTHER |
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A retrospective analysis of all patients that underwent carotid endarterectomy (CEA) for stenotic disease - diagnosed at pre-operative investigation - prior to CABG as staged operation within 6- months.
The rate of postoperative stroke and complications was compared between CEA performed under Local anaesthetic (LA) to those performed under General anaesthetic (GA).
The primary outcome was the rate of postoperative stroke in patients that had staged CEA prior to CABG. This was defined as CEA within a period of 4 weeks prior to CABG.
We retrospectively looked at those patients that fulfilled the inclusion criteria and had CEA performed either under LA (Group A) or under GA (Group B). We measured the 30 days' postoperative stroke rate as the main outcome. We also looked at the rate of intraoperative stroke.
Additionally, we assessed the rate for developing nerve injuries and/or hematoma postoperatively. Finally, we examined the risk for developing postoperative stroke in patients with bilateral significant carotid artery disease that underwent surgery in one side.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Carotid Endarterectomy under Local Anaesthetic Pre-CABG | Patients that underwent carotid endarterectomy under local anaesthetic prior to coronary artery bypass operations in staged fashion within 6 months. |
| |
| Carotid Endarterectomy under General Anaesthetic Pre-CABG | Patients that underwent carotid endarterectomy under general anaesthetic prior to coronary artery bypass operations in staged fashion within 6 months. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Carotid endarterectomy | Procedure | Carotid endarterectomy prior to CABG operations either under Local Anaesthetic or under General Anaesthetic. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Stroke | a transient ischaemic attack (TIA), or a disabling stroke within 30 days of the carotid endarterectomy procedure. | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Major bleeding | Major haematoma was defined as a significant bleeding that required the patient to go back to theatre for a secondary procedure. | 30 days |
| Minor bleeding | A minor hematoma was defined as bleeding that resulted in bruising and neck swelling without causing significant concerns to require a secondary procedur |
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Inclusion Criteria:
- All patients that had carotid endarterectomy performed in staged fashion within 6 months before a CABG operation.
Exclusion Criteria:
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In-hospital patients referred by Cardiothoracic for carotid endarterectomy prior to CABG.
Hospital records not to be shared, but raw data used for statistical analysis will be shared after removing identifiers.
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| ID | Term |
|---|---|
| D002340 | Carotid Artery Diseases |
| D003324 | Coronary Artery Disease |
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D016894 | Endarterectomy, Carotid |
| ID | Term |
|---|---|
| D004691 | Endarterectomy |
| D014656 | Vascular Surgical Procedures |
| D013504 | Cardiovascular Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| 30 days |
| Nerve injuries | Either neuropraxia that resolved with time or permanent injuries that resulted in disability. | 30 days |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |