recruitment difficulties

The main hypothesis is that a significant pain improve (measured with Visual Analogic Scale [VAS]) can be observed after injection of botulinum toxin A, meaning the success of the guidance device.

Inclusion Criteria:

• patients suffering from muscular TemporoMandibular Dysfunctions (TMD) with clinical diagnosis: myofascial pain, limited opening of the mouth, articular noise.
• >= 18 years old
• with signed informed consent form

Exclusion Criteria:

• articular TMD: arthritis or other inflammatory disease of temporomandibular joint, arthrosis, bone deformation, previous fracture of condylar area ;
• electromyographic hypoactivity, pure muscular diseases ;
• oro-mandibular dystonia ;
• botulinum toxin allergy,
• risk of bleeding
• recent or active infection
• intercurrent antibiotic treatment (drug interaction) ;
• vaccination during the 15 days preceding the injection.