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The aim of this study was to observe the effect of hormonal treatment (oral or transdermal substitution therapy) on diuresis (salt and water diuresis) and lower urinary tract symptoms (LUTS) in postmenopausal women
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hormonal therapy | Experimental | Patients choosing to start hormoanl treatment using ural or transdermal estrogen. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ICIQ FLUTS Questionaires | Diagnostic Test | Questionnaire observing the impact on voiding disfunctions |
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| Measure | Description | Time Frame |
|---|---|---|
| Change of HT on nocturnal frequency | Change of nocturnal frequency by 1 nocturnal void after 6 months of hormonal treatment. | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Effect on nocturnal urine production | Change of the nocturnal urine production by hormonal treatment by the volume of one micturition (+- 200ml) | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Menopausal women
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35550708 | Derived | Pauwaert K, Bruneel E, Van Laecke E, Depypere H, Everaert K, Goessaert AS. Does hormonal therapy affect the bladder or the kidney in postmenopausal women with and without nocturnal polyuria: Results of a pilot trial? Maturitas. 2022 Jun;160:61-67. doi: 10.1016/j.maturitas.2022.01.009. Epub 2022 Jan 29. |
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| ID | Term |
|---|---|
| D053158 | Nocturia |
| ID | Term |
|---|---|
| D059411 | Lower Urinary Tract Symptoms |
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D006403 | Hematologic Tests |
| ID | Term |
|---|---|
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D008919 | Investigative Techniques |
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| Frequency Volume Chart | Diagnostic Test | Frequency Volume Chart measures the voided volumes and fluid intake during 3 days in order to observe patients bladder capacity, total and nighttime voided volume and voiding frequency |
|
| Renal Function Profile | Diagnostic Test | The RFP is a 24-hour urine analysis in which urine samples are collected at fixed time points every 3 hours, starting 3 hours after the first morning void. This RFP was collected on a separated day to the FVC. Daytime samples were taken between 10:00-11:30 (U1), 13:00-15:30 (U2), 16:00-17:30 (U3), 19:00-20:30 (U4), and 22:00-23:30 (U5). The night-time samples were taken between 1:00-2:30 (U6), 4:00-5:30 (U7) and 7:00-8:30 (U8), and the volume of each interim void, was noted to calculate the 24h, daytime and night-time urine volume and diuresis rate. On each of this 8 samples, creatinine, osmolality, sodium and urea concentration were analysed. Subsequently, the renal clearance of creatinine, solutes, sodium and potassium (Usubst x Uflow / Psubst) and FWC (urine flow - solute clearance) were calculated. |
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| Blood Analysis | Diagnostic Test | Blood analysis in order to observ postmenopausal state, osmolalitity and sodium. |
|