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The purpose of this study is to evaluate the use of personal genomic educational testing (PGET) on student knowledge and clinical skills surrounding pharmacogenomic testing to ensure it is of educational benefit to our student population. Students will be provided the opportunity to opt-in to test their own pharmacogenomic panel while participating in the standard curriculum. Students will have the option of using their own reports or dummy reports during classroom activities. Our hypothesis is that those students who have their own pharmacogenomics tested will show better overall performance.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Personal genomic educational testing (PGET) | Active Comparator | PGET group participants received their own pharmacogenomic testing results prior to the course modules covering material tested in the knowledge assessment |
|
| No personal genomic educational testing (NPGET) | Placebo Comparator | No PGET (NPGET) group participants did not receive their own pharmacogenomic testing results until after study completion. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Personal genomic educational testing (PGET) | Genetic | PGET consisted of a panel of pharmacogenomic variants |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Pharmacogenomics Knowledge Assessment | Improvement in performance on a knowledge assessment including eleven questions | 8-12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Self Assessment Questionnaire | Improvement in Likert Scale Responses for 27 questions (scale of 1[worst] to 6[best]) | 8-12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Nov 1, 2021 | |
| Reset | Dec 17, 2021 | |
| Release | Dec 10, 2024 | |
| Reset | Jan 23, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Nov 1, 2021 | Dec 17, 2021 | |||
| Dec 10, 2024 |
We investigated the effect of PGET on student knowledge, comfort, and attitudes related to pharmacogenomics (PGx) in a non-blinded, randomized controlled trial. Consenting participants were randomized to receive PGET or no PGET (NPGET) during four subsequent years of a PGx course.
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Instructors and all study personnel were blinded to participant PGET assignment, PGx results, and survey results.
| No personal genomic educational testing (NPGET) | Genetic | Lack of pharmacogenomic testing |
|
| Jan 23, 2025 |