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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A03370-39 | Other Identifier | IDRCB number |
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| Name | Class |
|---|---|
| URC-CIC Paris Descartes Necker Cochin | OTHER |
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Anatomical ophthalmological connections and their dynamics are still debated in the scientific community. However, their considering is essential in many surgeries (strabismus, cataract, refractive...) or in clinical practice.
The correlation between these biometric values would make it possible to refine the knowledge related to these landmarks and thus offer better ophthalmological management by integrating these variables into the clinical examination.
The aim of the study is to analyze the correlation between the angle alpha and the angle kappa in a healthy individual without ophthalmologic disorder.
The angle kappa corresponds to the angle formed between the visual axis (line between the point of fixation and the fovea: area of the retina allowing precise vision) and the pupillary axis (line passing through the center of the pupil and perpendicular to the cornea). The angle alpha corresponds to the angle formed between the visual axis and the optical axis (line passing through the nodal point of the eye and corneal center).
In theory, the angle kappa and angle alpha are equal; but physiological corectopy in the nasal position induces a variation between these two angles; the angle kappa being generally less than the angle alpha without a correlation being established. Also, pupillary constriction causes a variation in the position of the center of the pupil. The angle kappa therefore exhibits a variation depending on the expansion.
Anatomical ophthalmological connections and their dynamics are still debated in the scientific community. However, their considering is essential in many surgeries (strabismus, cataract, refractive ...) or in clinical practice.
The correlation between these biometric values would make it possible to refine the knowledge related to these landmarks and thus offer better ophthalmological management by integrating these variables into the clinical examination.
The aim of the study is to analyze the correlation between the angle alpha and the angle kappa in a healthy individual without an eye disorder.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy individual | Healthy individual |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Eye examination | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Value of the angle Kappa | Semi-automatic digital method of measurement by eye photography | Day 0 |
| Value of the angle Alpha | Semi-automatic digital method of measurement by eye photography | Day 0 |
| Measure | Description | Time Frame |
|---|---|---|
| Variation of the Kappa angle depending on the pupillary diameter | Variation in the same individual. Value of the Kappa angle using the semi-automatic method of measurement by ocular photography in photopic and scotopic conditions & measurement of the pupillary diameter using the photographs obtained | Day 0 |
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Inclusion Criteria:
- Informed major subject not opposing to their participation in the study
Exclusion Criteria:
- Subject with strabismus or organic ophthalmologic pathology
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Healthy individuals without visual disorders
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| Name | Affiliation | Role |
|---|---|---|
| Maxence Rateaux | Assistance Publique - Hôpitaux de Paris | Principal Investigator |
| Dominique Brémond-Gignac, MD, PhD | Assistance Publique - Hôpitaux de Paris | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Necker-Enfants Malades | Paris | 75015 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40810703 | Result | Rateaux M, Vienne-Jumeau A, Bremond-Gignac D, Robert MP. Fluctuations in angle lambda with the pupil diameter and correlations with biometric values in a healthy population. Ophthalmic Physiol Opt. 2025 Nov;45(7):1837-1844. doi: 10.1111/opo.70006. Epub 2025 Aug 14. | |
| 35731900 | Result | Rateaux M, Bremond-Gignac D, Robert MP. From monocular photograph to angle lambda: A new clinical approach for quantitative assessment. J Binocul Vis Ocul Motil. 2022 Jul-Sep;72(3):169-175. Epub 2022 Jun 22. |
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| Correlation between the value of the angle Alpha and the Optic disc / fovea distance |
Angle Alpha value using the semi-automatic method of measurement by eye photography and the distance between the optic disc and the fovea |
| Day 0 |
| Correlation between the angle Kappa and the axial length | Value of the angle Kappa and Alpha using the semi-automatic method of measurement by eye photography and Value of the axial length measured by biometry IolMaster 500 (Carl Zeiss) | Day 0 |