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Overloading is a key training principle used by athletes and coaches to improve physical performance. Intensified training periods are therefore commonly incorporated into the course of a regular training season. From a clinical point of view, very intense periods of training are associated with a temporary immunological deficiency which can lead to teh "overreaching syndroms".
During periods of overreaching, nutritional strategies are mainly aimed at ensuring sufficient amounts of energy to support the increase in effort. However less is known about nutritional supplements to attenuated the inflammatory/immunological response to training stress.
Probiotic bacteria are defined as live food ingredients beneficial to the host's health. Numerous health benefits have been attributed to probiotics, including effects on gastrointestinal tract function and disease, immune function, hyperlipidemia, hypertension, and allergic conditions. Studies in the literature on the ergogenic effect of probiotics in athletes are still scarce today. this study aims to explore the potential role of probiotics on performance, recovery from fatigue and immune function during intensive period of training.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Probiotics | Experimental | participants will train for 15 days while consuming the dietary supplement. During the last 8 days the intensity of training will increase to induce overreaching. |
|
| Placebo | Placebo Comparator | participants will train for 15 days while consuming the dietary supplement. During the last 8 days the intensity of training will increase to induce overreaching. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| probiotics | Dietary Supplement | participants will be given probiotics twice a day for 15 days |
| |
| Measure | Description | Time Frame |
|---|---|---|
| lymphocyte subpopulation total T (CD3+) | lymphocyte subpopulation: total T (CD3+) % | Change from baseline to up to 15 days |
| T-helper (CD4+) | lymphocyte subpopulation: T-helper (CD4+) % | Change from baseline to up to 15 days |
| T-suppressor (CD8+) | lymphocyte subpopulation: T-suppressor (CD8+) % | Change from baseline to up to 15 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tatiana Moro, PhD | Contact | 0498275306 | tatiana.moro@unipd.it |
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| ID | Term |
|---|---|
| D005221 | Fatigue |
| ID | Term |
|---|---|
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| placebo |
| Dietary Supplement |
participants will be given a placebo twice a day for 15 days |
|
| D019602 |
| Food and Beverages |