The CorPath GRX System is intended for use in the remote delivery and manipulation of guidewires and rapid exchange catheters, and remote manipulation of guide catheters during percutaneous coronary and vascular procedures.

TechnIQ automated movements are software-based automation of common maneuvers that interventionalists perform when manipulating catheters, guidewires, and devices by hand. In this group, automated movements will be disabled.

Reported as a composite and components of Cardiac Death, Target Vessel MI, and Target Vessel Revascularization (TVR).

Reported as perforation(Type 1, 2, 3) or flow-limiting dissection (Type E, F).

All Serious Adverse Events (SAEs) from the start of the CorPath GRX PCI procedure through 72 hours postprocedure or hospital discharge (whichever occurs) first will be summarized

The time required to advance the guidewire from the tip of the guide catheter to the final target distal to the lesion.

The fluoroscopy time required to advance the guidewire from the tip of the guide catheter to the final target distal to the lesion.

The amount of contrast (in ml) required to advance the guidewire from the tip of the guide catheter to the final target distal to the lesion.

The time from the start of the sheath insertion to complete removal of the final guide catheter.

The total fluoroscopy time during the procedure as recorded by an Imaging System.

Dose-area-product (DAP) as recorded during the procedure

air kerma (AK) as recorded during the procedure.

The total contrast volume used during the procedure.

Planned manual conversion (PMC) is disengagement of the robotic drive to use bedside manipulation of either the guide catheter, guidewire, or delivery system that was prespecified in the procedural plan (e.g., to accommodate adjunctive devices or procedural techniques that are not compatible with the robotic platform, such as intravascular ultrasound or atherectomy devices). This will be assessed by a questionnaire.

Unplanned manual conversion (UMC) is disengagement of the robotic drive to use bedside manipulation of either the guide catheter, guidewire, or delivery system that was not prespecified in the procedural plan, and that was due to inability to navigate to the target lesion as intended, cross the target lesion as intended, treat the target lesion as intended, retract the CorPath GRX system as intended, or other CorPath system device malfunction; or any clinical condition that requires rapid medical intervention. This will be assessed by a questionnaire.

Partial manual assistance (PMA) is the use of manual techniques that were not prespecified in the procedural plan and do not meet the definition of unplanned manual conversion (e.g., unplanned use of manual techniques to accommodate adjunctive devices or procedural techniques that are not compatible with the robotic platform). These will be assessed by a questionnaire.

The device malfunction will report the inadequacy of the medical device with respect to its identity, quality, durability, reliability, usability, safety, or performance. Investigators are instructed to report all device deficiencies and device malfunctions using the device malfunction form in the EDC.