Pressurised intraperitoneal aerosol chemotherapy is a new surgical technique, developed for the treatment of initially unresectable peritoneal carcinomatosis. The objective of this study was to compare the results of PIPAC associated with systemic chemotherapy with those of systemic chemotherapy alone in patients with gastric peritoneal carcinomatosis without metastasis other than peritoneal, and WHO performance status <3.

Inclusion Criteria:

• Patients 18 years or over
• Patients with adenocarcinoma-type gastric non-resectable péritonéale carcinomatosis.
• Patients without metastasis other than peritoneal.
• WHO performance status <3
• Patients treated either with PIPAC administered in alternation with systemic chemotherapy (PIPAC_CHEM) or by systemic chemotherapy alone (ONLY_CHEM)
• Patient informed

Exclusion Criteria:

- Patients opposed

The study population consisted of adult patients with adenocarcinoma-type gastric non-resectable PC, without metastasis other than peritoneal, treated either with PIPAC administered in alternation with systemic chemotherapy or by systemic chemotherapy alone. All patients receiving PIPAC in our hospital during the study period were included. The patients in the group had been treated during the same period and were carefully selected according to age, general state of health (WHO performance status <3) and absence of extra-peritoneal metastases so as to match as closely as possible the patients in the PIPAC group.