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| ID | Type | Description | Link |
|---|---|---|---|
| WT762123 | Other Identifier | Oxford Brookes University |
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| Name | Class |
|---|---|
| Roquette Freres | INDUSTRY |
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A comparison of the glycaemic response and insulinaemic response to glucose, Nutralys S85 Plus pea protein and whey protein using a single-blind, randomised, repeat measure, crossover design trial.
A single-blind, randomised, repeat measure, crossover design trial will be used to study the glycaemic response and insulinaemic response following consumption of five products: one reference product (50 g available carbohydrate Glucose) and four test products (50 g available carbohydrate Glucose with 10 g NUTRALYS®S85 Plus pea protein, 50 g available carbohydrate Glucose with 20 g NUTRALYS®S85 Plus pea protein, 50 g available carbohydrate Glucose with 10 g Whey protein concentrate and 50 g available carbohydrate Glucose with 20 g Whey protein concentrate).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Glucose | Placebo Comparator | Glucose 50 g available carbohydrate |
|
| 10 g NUTRALYS®S85 Plus pea protein | Experimental | 50 g available carbohydrate Glucose + 10 g NUTRALYS®S85 Plus pea protein |
|
| 20 g NUTRALYS®S85 Plus pea protein | Experimental | 50 g available carbohydrate Glucose + 20 g NUTRALYS®S85 Plus pea protein |
|
| 10 g Whey protein concentrate | Experimental | 50 g available carbohydrate Glucose + 10 g Whey protein concentrate |
|
| 20 g Whey protein concentrate | Experimental | 50 g available carbohydrate Glucose + 20 g Whey protein concentrate |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 10 g NUTRALYS®S85 Plus pea protein | Dietary Supplement | To determine the glycaemic response and insulinaemic response to 50g Glucose + 10 g NUTRALYS®S85 Plus pea protein. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in blood glucose response from baseline for 3 hours | Change in postprandial blood glucose response from baseline was measured at 15 min, 30 min, 45 min, 1 hour, 1.5 hours, 2 hours, 2.5 hours and 3 hours | 3 hours |
| Change in plasma insulin response from baseline for 3 hours | Change in postprandial plasma insulin response from baseline was measured at 15 min, 30 min, 45 min, 1 hour, 1.5 hours, 2 hours, 2.5 hours and 3 hours | 3 hours |
| Area under the blood glucose concentration versus time curve | Area under the blood glucose concentration versus time curve was calculated by trapezoidal rule | 3 hours |
| Area under the plasma insulin concentration versus time curve | Area under the plasma insulin concentration versus time curve was calculated by trapezoidal rule | 3 hours |
| Peak blood glucose concentration (Cmax) | Peak blood glucose concentration (Cmax) after consumption of the test food | 0-3 hours |
| Peak plasma insulin concentration (Cmax) | Peak plasma insulin concentration (Cmax) after consumption of the test food | 0-3 hours |
| Time of blood glucose peak (Tmax) | Time of blood glucose peak after consumption of the test food | 0-3 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sangeetha Thondre, PhD | Oxford Brookes University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Oxford Brookes Centre for Nutrition and Health | Oxford | OX3 0BP | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20359723 | Background | Siahanidou T, Margeli A, Kappis A, Papassotiriou I, Mandyla H. Circulating visfatin levels in healthy preterm infants are independently associated with high-density lipoprotein cholesterol levels and dietary long-chain polyunsaturated fatty acids. Metabolism. 2011 Mar;60(3):389-93. doi: 10.1016/j.metabol.2010.03.002. Epub 2010 Mar 31. |
| Label | URL |
|---|---|
| Food Products-Determination of the glycaemic index (GI) and recommendation for food classification. | View source |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| ICF | No | No | Yes | Informed Consent Form | Aug 25, 2020 | Apr 29, 2021 | ICF_000.pdf |
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| ID | Term |
|---|---|
| D000078724 | Pea Proteins |
| D000067796 | Whey |
| D005947 | Glucose |
| ID | Term |
|---|---|
| D014674 | Plant Proteins, Dietary |
| D004044 | Dietary Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
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single-blind, randomised, repeat measure, crossover design trial
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single-blind
| 20 g NUTRALYS®S85 Plus pea protein | Dietary Supplement | To determine the glycaemic response and insulinaemic response to 50g Glucose + 20 g NUTRALYS®S85 Plus pea protein. |
|
| 10 g Whey protein concentrate | Dietary Supplement | To determine the glycaemic response and insulinaemic response to 50g Glucose + 10 g Whey protein concentrate. |
|
| 20 g Whey protein concentrate | Dietary Supplement | To determine the glycaemic response and insulinaemic response to 50g Glucose + 20 g Whey protein concentrate. |
|
| 50 g Glucose | Dietary Supplement | To determine the glycaemic response and insulinaemic response to 50g Glucose |
|
| Time of plasma insulin peak (Tmax) | Time of plasma insulin peak after consumption of the test food | 0-3 hours |
| D010940 |
| Plant Proteins |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
| D008892 | Milk |
| D001628 | Beverages |
| D003611 | Dairy Products |
| D006601 | Hexoses |
| D009005 | Monosaccharides |
| D000073893 | Sugars |
| D002241 | Carbohydrates |