Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 1IK2RX003520-01A2 | U.S. NIH Grant/Contract | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Individual with anxiety and post-traumatic stress disorder often use alcohol in ways that could cause them harm. Treating both mental health concerns and alcohol use at the same time can help reduce difficulties engaging in multiple treatments. The investigators are evaluating how a cognitive behavioral therapy program that helps Veterans with anxiety, posttraumatic stress disorder, and alcohol use at the same time can help improve the participants lives.
Co-occurring hazardous drinking, anxiety disorders, and PTSD are problematic combinations of mental health concerns experienced by deployed Veterans. Veterans who have been deployed are at particular risk for experiencing problems in functioning and reintegration related to mental health disorders and hazardous drinking. Co-occurring anxiety and hazardous drinking heavily impact psychosocial functioning and quality of life. Although cognitive behavior therapy (CBT) can promote psychological recovery through improvements in functioning and quality of life, most CBT protocols do not address co-occurring disorders, leading to inefficient and disjointed treatment. The current research seeks to adapt and test the Unified Protocol (UP) for deployed Veterans with hazardous drinking. The use of combined CBT for both anxiety disorders and hazardous drinking has the potential to more efficiently and effectively improve functioning, reduce symptoms, and promote psychosocial recovery.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| UP-A | Experimental | Cognitive behavior therapy using the Unified Protocol for Emotional Disorders with supplemental skills-based alcohol modules. |
|
| Enhanced Usual Care | Active Comparator | referrals to VA care for SUD and anxiety |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Unified Protocol- Alcohol | Behavioral | Transdiagnostic cognitive behavior therapy for emotional disorders modified to include CBT for alcohol use. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Social Adjustment Scale- Self Report | Evaluates individuals' satisfaction with social situation. Greater scores reflect greater social/occupational impairment (range 42-210). | 2-weeks |
| Beck Anxiety Inventory | Evaluates levels of anxiety in past month. Higher scores reflect greater anxiety (range 0-63). | past 30 days |
| Addiction Severity Index | Assessment of substance use and related problems. Higher scores in each domain indicate problems related to substance use in that domain (range for each domain 0-1). | 30 days |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
-need for acute medically-supervised detoxification with exclusionary criteria of
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Anthony Ecker, PhD | Michael E. DeBakey VA Medical Center, Houston, TX | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Michael E. DeBakey VA Medical Center, Houston, TX | Houston | Texas | 77030-4211 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| ICF | No | No | Yes | Informed Consent Form | Aug 25, 2025 | Jun 5, 2026 | ICF_000.pdf |
Not provided
| ID | Term |
|---|---|
| D001008 | Anxiety Disorders |
| D013313 | Stress Disorders, Post-Traumatic |
| D000428 | Alcohol Drinking |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D004327 | Drinking Behavior |
Not provided
Not provided
| ID | Term |
|---|---|
| D000431 | Ethanol |
| ID | Term |
|---|---|
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
Not provided
Not provided
Participants will be randomized to receive the intervention or a control intervention.
Not provided
Not provided
Not provided
Not provided
| Usual care | Behavioral | referrals to VA care for SUD and anxiety |
|
| D001519 | Behavior |